The effect of 900-MHz radiofrequency electromagnetic fields during the adolescence on the histological structure of rat testis and its androgen and estrogen receptors localization

Gür, Fatih Mehmet; Keleş, Ayşe İkinci; Erol, Hüseyin Serkan; Güven, Cengiz; Taşkın, Eylem; Kaya, Haydar; Gür, Hatice Emel; Odacı, Ersan; Halici, Mesut; Timurkaan, Sema

doi:10.29252/ijrr.19.1.135

Cited by 9 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the study, no difference was observed in sperm motility and concentration of the exposure group rats (Taş et al, 2014). In another study, it was reported that 900 MHz RF electromagnetic field could cause oxidative stress in the testicles of rats and that this situation was quite low for testicular damage (Gür et al, 2021). They stated that 900 MHz RF-EMF exposure for 20 minutes a day for three weeks may cause oxidative damage to the testicular tissue by affecting the antioxidant defense system (Eşmekaya et al, 2011).…”

Section: Effect Of 900 Mhz Radiofrequency Radiation On the Male Repro...mentioning

confidence: 82%

Dalak Anatomisi ve Klinik Önemi

Erbek,

Bolatlı

2023

Sağlık Bilimleri Araştırmaları: Temel Tıp- IV

View full text Add to dashboard Cite

Dalak, regio hypochondriaca sinistra’da yer alan intraperitoneal bir organdır. Hematolojik ve immünolojik rolü nedeniyle klinik önem taşımaktadır. Yaralanma insidansı en yüksek olduğu sol kaburga kırıklarında yırtılma ile meydana gelen rüptürün periton boşluğunda aşırı kanamaya sebep olduğundan kısmi veya tam splenektomi durumları görülebilmektedir. Dalağın lobülasyonu veya aksesuar dalak gibi bazı konjenital varyasyonları yaygın olarak görülebilmektedir. Splenektomi çeşitli cerrahi komplikasyonlara karşı savunmasızdır ve bu nedenle cerrahların dalak dokusunu verimli bir şekilde korumalı ve muhafaza etmelidirler. Laparoskopik splenektomi normal ve orta derecede genişlemiş dalaklar için standart splenektomi yöntemidir. Daha büyük dalaklarda, açık splenektomiye alternatif bir tedavi seçeneği olmaktadır.

show abstract

Section: Effect Of 900 Mhz Radiofrequency Radiation On the Male Repro...mentioning

confidence: 82%

Dalak Anatomisi ve Klinik Önemi

Erbek,

Bolatlı

2023

Sağlık Bilimleri Araştırmaları: Temel Tıp- IV

View full text Add to dashboard Cite

show abstract

“…Apoptosis was identified by evaluating deparaffinised testicular tissue sections by TUNEL analysis as described previously (Gur et al, 2021). For this, In Situ Cell Death Detection Kit (Roche) was used according to the manufacturer's instructions.…”

Section: Tunel (Terminal Deoxynucleotidyl Transferase Dutp Nick-end Labelling) Analysismentioning

confidence: 99%

Thymoquinone improves testicular damage and sperm quality in experimentally varicocele‐induced adolescent rats

et al. 2021

View full text Add to dashboard Cite

The aim of this study was to investigate the protective and therapeutic effects of thymoquinone against the negative effects of varicocele on testicular tissue and sperm morphology. Five groups were formed by random selection from a total of 40 adult male Wistar rats (n = 8). Thymoquinone (5 mg/kg/day) was administered intraperitoneally to the varicocele‐dimethyl sulfoxide‐olive oil‐thymoquinone (VT) group and the sham‐thymoquinone group. At the end of the 60th day, all groups were anaesthetised and the left testis was removed from the body quickly. One half of the testis tissue, which was divided into two, was separated for biochemical and Western blot analysis, while the other half were fixed in Bouin's fixative. As a result of biochemical, molecular and histopathological analyses, a statistically significant increase was found in the varicocele group testicular tissues in the malondialdehyde level, apoptotic index, Bax expression, cytochrome c expression and Bax/Bcl‐2 ratio compared with the sham group. In addition, histopathological changes characterised by partial or complete degeneration of the germinal epithelium were observed in the seminiferous tubules in the same group. Total oxidant status level and sperm count with abnormal morphology increased in varicocele group, whereas total antioxidant status level decreased. In the VT group, all of the biochemical, molecular and histopathological changes detected in the varicocele group were statistically significantly reduced. When the findings obtained in this study are evaluated, it can be said that thymoquinone has the potential to be used as a preventive and therapeutic pharmacological agent in the medical treatment of varicocele. Although the exact mechanism of action of thymoquinone has not been fully elucidated, the findings obtained in this study support the view that thymoquinone showed a cytoprotective effect by reducing apoptosis, oxidative stress and lipid peroxidation.

show abstract

Promising the potential of β-caryophyllene on mercury chloride–induced alteration in cerebellum and spinal cord of young Wistar albino rats

Yahyazadeh,

Gur

2024

Naunyn-Schmiedeberg's Arch Pharmacol

View full text Add to dashboard Cite

Mercury chloride (ME) is a chemical pollutant commonly found in the environment, which can contribute to undesirable health consequence worldwide. The current study investigated the detrimental impact of ME on the cerebellum and spinal cord tissues in 6–8-week-old female rats. We also evaluated the neuroprotective efficacy of β-caryophyllene (BC) against spinal and cerebellar changes caused by ME. Thirty-five young Wistar albino rats were randomly chosen and assigned into five groups: control (CO), olive oil (OI), ME, BC, ME + BC. All samples were analysed by means of unbiased stereological, biochemical, immunohistochemical, and histopathological methods. Our biochemical findings showed that SOD level was significantly increased in the ME group compared to the CO group (p < 0.05). We additionally detected a statistically significant decrease in the number of cerebellar Purkinje cells and granular cells, as well as spinal motor neuron in the ME group compared to the CO group (p < 0.05). In the ME + BC group, the number of Purkinje cells, granular cells, and spinal motor neurons was significantly higher compared to the ME group (p < 0.05). Decreased SOD activity in the ME + BC group was also detected than the ME group (p < 0.05). Immunohistochemical (the tumour necrosis factor-alpha (TNF-α)) and histopathological examinations also exhibited crucial information in each of the group. Taken together, ME exposure was associated with neurotoxicity in the cerebellum and spinal cord tissues. BC treatment also mitigated ME-induced neurological alteration, which may imply its potential therapeutic benefits.

show abstract

The effect of 900-MHz radiofrequency electromagnetic fields during the adolescence on the histological structure of rat testis and its androgen and estrogen receptors localization

Cited by 9 publications

References 0 publications

Dalak Anatomisi ve Klinik Önemi

Dalak Anatomisi ve Klinik Önemi

Thymoquinone improves testicular damage and sperm quality in experimentally varicocele‐induced adolescent rats

Promising the potential of β-caryophyllene on mercury chloride–induced alteration in cerebellum and spinal cord of young Wistar albino rats

Contact Info

Product

Resources

About