The Effect of 8 Weeks Rhythmic Aerobic Exercise on Vaspin Levels and Lipid Profile in Overweight and Obese Women

Abstract

Obesity as a chronic disease causes many diseases. Vaspin is a new adipokine, which increase as a result of inflammation resulting from obesity and metabolic diseases (3). Regular exercise has a variety of benefits, including increasing insulinsensitivity, controlling blood sugar (glucose), losing weight, decreasing body fat percentage, reducing inflammation stress. Kadoglou et al. (2013) (P = 0.000), vaspin (P = 0.003), HDL (P = 0.000), LDL (P = 0.001), and TC (P = 0.001), while had no significant effect on TG (P = 0.692

Exercise training modulates adipokine dysregulations in metabolic syndrome

“…and Shahdadi et al. 135 , 149 showed a reduction in serum vaspin levels after AT in obese subjects. In contrast, a higher vaspin level has been found following 4-week AT in obese and T2D subjects.…”

“…Similar to AT, vaspin serum level is changed differently in response to RT. For example, two studies reported a significant reduction in serum vaspin level following RT in obese individuals, 135 , 149 in contrast with Mahdirejei et al. 150 who reported no significant alteration.…”

“… 151 It seems that vaspin serum concentration might be differentially regulated in an enzyme (nicotinamide phosphoribosyl transferase enzyme)-dependent manner. 135 , 149 The exact signaling pathways by which AT and RT suppress vaspin production needs more investigation.…”

The effects of physical activity on adipokines in individuals with overweight/obesity across the lifespan: A narrative review

“…280 Similarly, other studies reported significant decreases in vaspin levels after rhythmic aerobic exercise or rhythmic aerobic exercise plus core stability training in females with overweight and/or obesity. 277,281,282 However, a cross-sectional study found no significant differences in vaspin levels between control adolescent male subjects and individuals with obesity (BMI ≥ 25) subjected to 12 weeks of aerobic exercise. 283 However, vaspin levels were significantly associated with intima-media thickness, an early indicator of atherosclerosis.…”