The effect of 1% povidone iodine and 0,75% boric acid on chronic periodontitis treatment

Abstract

Objective: To evaluate the effect of 0,75% boric acid or 1% povidone iodine irrigation an adjunct to scaling and root planning (SRP) in treatment of chronic periodontitis patients. Methods: A singlemasked, randomized, clinical trial with 40 chronic periodontitis patients was selected at Facultly of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh city. They were randomly divided into two treatment groups depending on the irrigation solution: Group 1, SRP plus 1% PVP-I irrigation Group 2, SRP plus 0,75% boric acid irrigation. Clinical measurements including bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were obtained; and quantitative analyses of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg) were performed using real-time polymerase chain reaction (PCR) procedures at baseline (T0), 4 weeks (T4), 8 weeks (T8) and 12 weeks (T12) after periodontitis treatment. Results: The PD and CAL parameters in shadow, moderate and severe pockets; and amount of Aa, Pg showed statistically significant reduction at T4, T8, and T12 compared to T0 in both groups. Between the two groups, whole mouth BOP reduction was significantly bigger in group 2 compared to group 1 at T4, T8 and T12. The PD and CAL reductions were significantly greater in group 2 compared to group 1 at T4, and T8 and T12 for shadow, moderate and deep pockets; and at T4 for deep pockets. The reductions in amount of Aa, Pg were greater in group 2 compare to group 1 at T4, T8 and T12, however, statistical differences were not found. Conclusion: The results of this study suggest that 0,75% boric acid might be more effective than 1% povidone-iodine in treatment for patients with chronic periodontitis.

Effects of Rinsing with Povidone-Iodine during Step II Periodontal Therapy: A Systematic Review and Meta-Analysis

“…Supplement Table S1: Precise search strategy for the three databases (Embase, Cochrane and PubMed) with the boolean parameters used (overview from PubMed). Supplement Table S2: List with excluded studies after full text screening with reason for exclusion [59][60][61][62][63][64][65][66][67]. Supplement Figure S1: Funnel plot of the included studies in the review (in term of probing pocket depth after 6 months).…”