The Eff ect of Precursors and Elicitors on the Production of Oleanolic Acid in Suspension Culture of Lantana camara

Abstract

Oleanolic acid (OA) is an important pentacyclic triterpenoid. Traditionally used by Asian medicine, OA for anti-infl ammatory, anti-hyperlipidemic, and hepatoprotective. This study used triterpene precursors at 1 to 5 mg/L and elicitors in diff erent concentrations at 2, 5, 10 mg/L to enhance OA production in Lantana camara suspension cultures. Treated cells were evaluated for their OA contents by using HPLC and compared with the nontreated cells as a control. The results showed that FPP at 2 mg/L infl uenced the biomass and OA production more over the phytohormone combination, other precursors, and elicitors in Suspension cultures of L. camara.