The Economics of Age-Related Macular Degeneration

Brown, Gary C.; Brown, Melissa M.; Lieske, Heidi B.; Lieske, Philip A.; Brown, Kathryn

doi:10.1007/978-1-4614-0125-4_10

Age-Related Macular Degeneration Diagnosis and Treatment 2011

DOI: 10.1007/978-1-4614-0125-4_10

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The Economics of Age-Related Macular Degeneration

Gary C. Brown

Melissa M. Brown

Heidi B. Lieske

et al.

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Cited by 2 publications

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“…1,2 The burden of AMD on public health and the economy is expected to rise as a result of the progressive increase in the life expectancy and the proportion of elderly people in the population. [3][4][5] The identification and modification of risk factors related to AMD may improve knowledge regarding its pathogenesis, facilitating prevention, and subsequently reduce the morbidity associated with AMD.…”

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confidence: 99%

Diabetes Mellitus and Early Age-related Macular Degeneration

Choi

Lym²,

Moon³

et al. 2011

Arch Ophthalmol

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To examine the association of diabetes mellitus and early age-related macular degeneration (AMD) in Korean adults 50 years and older. Methods: This study included 3008 participants aged 50 to 87 years. Early AMD was assessed from retinal photographs based on a modified Wisconsin AMD grading system. Diabetes mellitus was defined as a fasting glucose level of 126 mg/dL or greater or the use of antidiabetic medications. Logistic regression was used to examine the association between diabetes mellitus and early AMD. Results: There were 88 subjects with early AMD and 315 subjects with diabetes mellitus. After adjusting for age, sex, current smoking, obesity, and hypertension, significant association was found between diabetes mellitus and early AMD. Subjects with diabetes mellitus were more likely to have early AMD (odds ratio, 1.87; 95% confidence interval, 1.07-3.28) than were those without diabetes mellitus. Conclusion: There is a relationship between diabetes mellitus and early AMD in Korean adults 50 years and older. The underlying biological processes remain to be determined.

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confidence: 99%

Diabetes Mellitus and Early Age-related Macular Degeneration

Choi

Lym²,

Moon³

et al. 2011

Arch Ophthalmol

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A Swine Model of Selective Geographic Atrophy of Outer Retinal Layers Mimicking Atrophic AMD: A Phase I Escalating Dose of Subretinal Sodium Iodate

Monés

Leiva

Peña

et al. 2016

Invest. Ophthalmol. Vis. Sci.

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The swine model of a controlled area of circumscribed retinal damage, with well-delimited borders, and selectively of the outer layers of the retina presented herein shows several clinical and histologic features of geographic atrophy in AMD. Therefore, it may represent a valuable tool in the investigation of new emerging regenerative therapies that aim to restore visual function, such as stem cell transplantation or optogenetics.

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The Economics of Age-Related Macular Degeneration

Cited by 2 publications

References 49 publications

Diabetes Mellitus and Early Age-related Macular Degeneration

Diabetes Mellitus and Early Age-related Macular Degeneration

A Swine Model of Selective Geographic Atrophy of Outer Retinal Layers Mimicking Atrophic AMD: A Phase I Escalating Dose of Subretinal Sodium Iodate

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