The Ecological and Evolutionary Implications of Pyrethroid Exposure: A New Perspective on Aquatic Ecotoxicity

Major, Kaley M.; Brander, Susanne M.

doi:10.1007/698_2019_432

Cited by 12 publications

(3 citation statements)

References 167 publications

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“…Some responses we detected are likely caused by heritable epigenetic modifications, mediated by changes in DNA methylation, which play an important role in the evolutionary process . While the molecular responses cannot directly be used toward explaining phenotypic outcomes, measurements conducted at various levels of biological organization, such as the ones presented in this study, serve as a weight of evidence of the impact of exposure to EDCs across multiple generations.…”

Section: Resultsmentioning

confidence: 97%

Multigenerational and Transgenerational Effects of Environmentally Relevant Concentrations of Endocrine Disruptors in an Estuarine Fish Model

DeCourten

Forbes

Roark

et al. 2020

Environ. Sci. Technol.

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Many pollutants cause endocrine disruption in aquatic organisms. While studies of the direct effects of toxicants on exposed organisms are commonplace, little is known about the potential for toxicant exposures in a parental (F0) generation to affect unexposed F1 or F2 generations (multigenerational and transgenerational effects, respectively), particularly in estuarine fishes. To investigate this possibility, we exposed inland silversides (Menidia beryllina) to environmentally relevant (low ng/L) concentrations of ethinylestradiol, bifenthrin, trenbolone, and levonorgestrel from 8 hpf to 21 dph. We then measured development, immune response, reproduction, gene expression, and DNA methylation for two subsequent generations following the exposure. Larval exposure (F0) to each compound resulted in negative effects in the F0 and F1 generations, and for ethinylestradiol and levonorgestrel, the F2 also. The specific endpoints that were responsive to exposure in each generation varied, but included increased incidence of larval deformities, reduced larval growth and survival, impaired immune function, skewed sex ratios, ovarian atresia, reduced egg production, and altered gene expression. Additionally, exposed fish exhibited differences in DNA methylation in selected genes, across all three generations, indicating epigenetic transfer of effects. These findings suggest that assessments across multiple generations are key to determining the full magnitude of adverse effects from contaminant exposure in early life.

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Section: Resultsmentioning

confidence: 97%

Multigenerational and Transgenerational Effects of Environmentally Relevant Concentrations of Endocrine Disruptors in an Estuarine Fish Model

DeCourten

Forbes

Roark

et al. 2020

Environ. Sci. Technol.

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“…85,86 Thus, these species act as important indicators of water quality in fish and shrimp aquaculture. 87 As indicated by genome analyses, the duplication of detoxification genes, including chemoreceptors, cytochrome P450, glutathione S-transferases, ATP-binding cassette proteins and metal sequestration proteins, has been interpreted as an evolutionary adaptation of H. azteca and T. japonicus to tolerate environmental toxicant exposure. 88,89…”

Section: Environmental Adaptationmentioning

confidence: 99%

“…Ecotoxicology : Many crustaceans, such as Daphnia spp., Hyalella azteca , and Tigriopus japonicus , have been used as models for ecotoxicology and evolutionary toxicology due to their sensitivity to toxicants 85,86 . Thus, these species act as important indicators of water quality in fish and shrimp aquaculture 87 . As indicated by genome analyses, the duplication of detoxification genes, including chemoreceptors, cytochrome P450, glutathione S‐transferases, ATP‐binding cassette proteins and metal sequestration proteins, has been interpreted as an evolutionary adaptation of H. azteca and T. japonicus to tolerate environmental toxicant exposure 88,89 …”

Section: Genome Signatures Underlying Specific Phenotypes Of Crustaceansmentioning

confidence: 99%

Recent advances in crustacean genomics and their potential application in aquaculture

Yuan

Zhang

et al. 2023

Reviews in Aquaculture

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Genomic resources are increasingly being used to improve the production efficiency and profitability of aquaculture. Crustaceans are a large group of invertebrates that encompasses some of the most important farmed species in the aquaculture industry. However, very few crustacean genomes have been published although an aquaculture genome project was proposed as early as 1997. Breakthroughs in next‐generation and third‐generation sequencing technologies and the development of high‐complexity sequence assembly strategies have promoted the publication of an increasing number of crustacean genomes, thus paving a broad way for biological and genetic studies and applications in aquaculture. In this review, we summarize recent advances in crustacean genomic research as of June 2022, including genome sequencing and assembly, genomic characteristics, and the genetic mechanisms underlying various biological phenotypes, such as environmental adaptation, lifestyle, development, and sex determination. This review also discusses the application of crustacean genomes in aquaculture, including genetic dissection of economic traits and genome‐based selective breeding via genome‐wide association studies and genomic selection. High‐quality genomes are important not only for understanding the genetic basis of biologically and economically important traits but also for the genetic improvement of aquaculture species. However, the utilization of crustacean genomics still lags far behind those in other animals. Therefore, additional multi‐omics studies and technological development are needed to accelerate the application of genomics in aquaculture.

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Presence of Contaminants of Emerging Concerns in the Environment

Brander,

Siddiqui

2024

Aquatic Ecotoxicology

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The Ecological and Evolutionary Implications of Pyrethroid Exposure: A New Perspective on Aquatic Ecotoxicity

Cited by 12 publications

References 167 publications

Multigenerational and Transgenerational Effects of Environmentally Relevant Concentrations of Endocrine Disruptors in an Estuarine Fish Model

Multigenerational and Transgenerational Effects of Environmentally Relevant Concentrations of Endocrine Disruptors in an Estuarine Fish Model

Recent advances in crustacean genomics and their potential application in aquaculture

Presence of Contaminants of Emerging Concerns in the Environment

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