1961
DOI: 10.1001/archderm.1961.01580180005001
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The Eccrine Sweat Glands of Patients in Uremia

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1963
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Cited by 41 publications
(18 citation statements)
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“…[210–12] Eighteen (64.26%) of our xerotic patients were known cases of diabetes mellitus and the ichthyosis involved large areas of the body as compared to other CRF patients. The pathogenesis of xerosis is unknown; various causes implicated include reduced sweat[13] secondary to high dose diuretic regimens used to treat CRF, elevated plasma vitamin A, elevated retinol binding protein,[14] alkalinity of skin,[15] and protein-calorie malnutrition[16] owing to dietary restrictions. The therapy remains nonspecific and challenging.…”
Section: Discussionmentioning
confidence: 99%
“…[210–12] Eighteen (64.26%) of our xerotic patients were known cases of diabetes mellitus and the ichthyosis involved large areas of the body as compared to other CRF patients. The pathogenesis of xerosis is unknown; various causes implicated include reduced sweat[13] secondary to high dose diuretic regimens used to treat CRF, elevated plasma vitamin A, elevated retinol binding protein,[14] alkalinity of skin,[15] and protein-calorie malnutrition[16] owing to dietary restrictions. The therapy remains nonspecific and challenging.…”
Section: Discussionmentioning
confidence: 99%
“…Xerosis and follicular hyperkeratosis are among the most commonly noted lesions in uremic patients (5,19). These disorders have multifactorial causes that are still largely unknown, but may be related to decreased function of the eccrine sweat glands (20) or to modifications of vitamin A use at the cellular level (2i). Both conditions are quite frequent in children.…”
Section: Discussionmentioning
confidence: 99%
“…Its prevalence was similar in patients on RHT (66%) and in those on CAPD (75%). The causes of this disorder are largely unknown, but it is possible that it may be referred to an impairment of eccrine sweat gland function [10]. Another possible cause of cutaneous xerosis could be an alteration of vitamin A metabolism.…”
Section: Discussionmentioning
confidence: 99%