The Early Onset Dementias: A Study of Clinical Characteristics and Service Use

Ferran, Jose; Wilson, Ken; Doran, Mark; Ghadiali, E; Johnson, Fiona; Cooper, Paul; McCracken, Cherie

doi:10.1002/(sici)1099-1166(199610)11:10<863::aid-gps394>3.0.co;2-7

Cited by 67 publications

(65 citation statements)

References 13 publications

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“…42 Evidence regarding the presence of behavioral and psychological symptoms of dementia (BPSD) was equivocal, with some studies reporting a higher presence for some subtypes such as FTD. 27,[43][44][45][46][47][48] However, BPSD were relatively common for most types adding to the needs and care requirements for people with YOD. 17,42 The most common BPSD for the EOAD group was apathy, 42 whereas aggression and disinhibition were more commonly reported for FTD.…”

Section: Epidemiological Studies Concerning Prevalence Incidence Anmentioning

confidence: 99%

“…17,42 The most common BPSD for the EOAD group was apathy, 42 whereas aggression and disinhibition were more commonly reported for FTD. 27,43,44 Some types of YOD such as Huntington's disease carry a high level of genetic transmission; Down syndrome carries a high risk for the development of dementia, and some forms of AD are more strongly associated with genetic risk factors. 49 For such affected groups, genetic counseling will be of prime importance.…”

Section: Epidemiological Studies Concerning Prevalence Incidence Anmentioning

confidence: 99%

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Younger Onset Dementia

Sansoni

Duncan

Grootemaat

et al. 2016

Am J Alzheimers Dis Other Demen

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This literature review focused on the experience, care, and service requirements of people with younger onset dementia. Systematic searches of 10 relevant bibliographic databases and a rigorous examination of the literature from nonacademic sources were undertaken. Searches identified 304 articles assessed for relevance and level of evidence, of which 74% were academic literature. The review identified the need for (1) more timely and accurate diagnosis and increased support immediately following diagnosis; (2) more individually tailored services addressing life cycle issues; (3) examination of the service needs of those living alone; (4) more systematic evaluation of services and programs; (5) further examination of service utilization, costs of illness, and cost effectiveness; and (6) current Australian clinical surveys to estimate prevalence, incidence, and survival rates. Although previous research has identified important service issues, there is a need for further studies with stronger research designs and consideration of the control of potentially confounding factors.

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Section: Epidemiological Studies Concerning Prevalence Incidence Anmentioning

confidence: 99%

Section: Epidemiological Studies Concerning Prevalence Incidence Anmentioning

confidence: 99%

Younger Onset Dementia

Sansoni

Duncan

Grootemaat

et al. 2016

Am J Alzheimers Dis Other Demen

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“…Diagnostic errors are also problematic given the prevalence of these two disorders (Dobie, 2002). DEP associated with cognitive symptoms, also sometimes referred to as pseudodementia, was found to represent 18% of referrals to a memory clinic, with the diagnosis missed by the majority of those referring the cases (Ferran et al, 1996); other researchers have reported an even larger proportion of individuals with pseudodementia, with 32-41% of dementia cases referred for psychiatric services eventually receiving a diagnosis of DEP with reversible cognitive changes (Maynard, 2003;Rabins, 1981). Likewise the growing prevalence of AD has been well established, with some regions of the United States expected to experience double-digit percentage increases in AD cases between the years 2000 to 2025 (Alzheimer's Association, 2009).…”

mentioning

confidence: 99%

Distinguishing clinical depression from early Alzheimer's disease in elderly people: Can narrative analysis help?

Murray

2010

Aphasiology

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Background: Differentiating the reversible cognitive symptoms associated with depression (DEP) from the irreversible dementia associated with early or mild Alzheimer's disease (AD) has proven to be challenging, particularly in elderly individuals. Most previous studies have focused on contrasting the cognitive profiles associated with these disorders, often yielding unreliable clinical differences. Although a limited set of studies have identified significant differences between DEP and early AD groups on both basic and high-level language production and comprehension tasks, none has included spoken discourse measures, and several limitations within these language studies indicate that further research is warranted. Aims: This study examined whether depression is associated with a distinct pattern of discourse changes, and thus whether discourse analyses may help discriminate elderly individuals with DEP from those in the early stages of AD. Methods & Procedures:Groups of elderly participants with DEP, mild AD, or no psychiatric or neurological diagnosis, who were matched for age and education level, completed a spoken narrative task and general cognition and high-level language tests. Quantitative, syntactic, and informativeness aspects of the discourse samples were analysed.Outcomes & Results: Significant group differences were observed on the informativeness discourse measures, with AD participants producing less-informative samples than DEP and control participants. DEP and control groups did not significantly differ on any discourse variable. Conclusions: Including discourse sampling and analyses, with a focus on informativeness, into comprehensive assessment protocols may lead to more accurate discrimination of DEP and early AD in the elderly.

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“…It published its 'Charter for younger people with dementia and their carers' which stated that all people with YOD, their families and carers should have access to specialist services from diagnosis to long term care. 15 The Alzheimer's Society and the Royal College of Psychiatrists published a joint policy document on YOD in 1999, recommending that local commissioning bodies appoint one named individual responsible for planning YOD services and one consultant acting as a focus for referrals. These two individuals would form the hub of the service, liaising with other people already involved in the provision of care for YOD, and developing ser vices appropriate to the region.…”

Section: Current State Of Care Deliverymentioning

confidence: 99%