The dynamics of bubble breakup in heart-shaped microchannels: Effect of structure

He, Wenzhuan; Zhu, Chunying; Fu, Taotao; Gao, Xiqun; Ma, Youguang; Li, Huai Z.

doi:10.1016/j.cej.2023.144302

Cited by 5 publications

(2 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, it is enough to change a parameter such as making sharper a corner of the heart-shaped unit of the aforementioned 2,000 or 10,000 t/a microfluidic flow reactors in SiC to achieve remarkable further improvements for instance in the mass transfer performance due the enhanced rapidity with which bubbles are broken into two or more sub-bubbles, enhancing the mixing of the two phases …”

Section: Resultsmentioning

confidence: 99%

Reshoring Fine Chemical and Pharmaceutical Productions

Ciriminna,

Della Pina,

Luque

et al. 2024

Org. Process Res. Dev.

View full text Add to dashboard Cite

Prolonged shortage of active pharmaceutical ingredients (APIs) in many countries that do not produce critically important APIs requires urgent reshoring of the said fine chemical productions. The situation is even worsened by frequent disruption of the global supply chains, first during the COVID-19 crisis and subsequently with the ongoing Red Sea crisis. In this study, we first outline the main economic and policy aspects emerging from selected cases of reshoring of API production to Europe. Hence, broadening the analysis to include selected cases in China and India, we investigate the industrial uptake of continuous manufacturing in fine chemicals production. Following said concrete analysis of the concrete situation, the study concludes with three main findings.

show abstract

Section: Resultsmentioning

confidence: 99%

Reshoring Fine Chemical and Pharmaceutical Productions

Ciriminna,

Della Pina,

Luque

et al. 2024

Org. Process Res. Dev.

View full text Add to dashboard Cite

show abstract

“…The ultrapure water used in the experiment was purchased from Shanghai Aladdin Biochemical Technology Co., Ltd., and N 2 was purchased from Tianjin Liufang Industrial Gas Distribution Co., Ltd. The surfactant sodium dodecyl sulfate (SDS) with a mass fraction of 0.3% was added to ultrapure water and dissolved as a continuous phase . N 2 is used as a dispersed phase.…”

Section: Methodsmentioning

confidence: 99%

Dynamics of Bubble Breakup in Improved AFRs with a Sharp Corner Structure

Chen,

He,

Zhao

et al. 2024

Ind. Eng. Chem. Res.

Self Cite

View full text Add to dashboard Cite

The influence of the sharp corner structure of the advanced flow reactor (AFR) heart-shaped unit developed by Corning Inc. on bubble breakup dynamics was visually investigated. It was found that the height and angle of the sharp corner structure in the AFR could significantly affect bubble breakup behavior and change the flow regime range. Three flow patterns were observed: non-breakup, breakup with partial obstruction, and breakup with permanent obstruction, among which breakup with permanent obstruction is the primary flow pattern. Under experimental conditions, when the height and the angle of the sharp corner are 0.4 mm and 90°, the range of the bubble breakup flow pattern is the widest. The bubble breakup process of breakup with permanent obstruction could be divided into the squeezing stage, the transition stage, and the rapid pinch-off stage. Furthermore, a correlation for predicting the period of bubble breakup in the AFR with a sharp corner structure is proposed.

show abstract

Splitting behavior and breakup mechanism of bubbles in the split‐and‐recombine microchannel

Chen,

Tian,

Zhang

et al. 2024

AIChE Journal

View full text Add to dashboard Cite

Split‐and‐recombine (SAR) microreactor is an advanced reactor for chemical process intensification. Bubble flow in the SAR microchannel is an important phenomenon that affects reaction efficiency, however drew little attention before. This study aims to explore the underlying mechanisms of bubble splitting, retraction, and breakup behaviors in a compact SAR microchannel. Two breakup flow patterns, unilateral flow and unilateral alternate flow were identified with symmetric or asymmetric splitting, respectively. Mechanism analysis indicates that the splitting symmetry issue is related to liquid slug size, viscous effect and novel retraction behavior of a splitting filament. The retraction is induced by the interconnection and unequal pressures between the splitting filaments. The correlation between normalized breakup time and Ca number confirms the Capillary‐pressure breakup mechanism for the splitting gas filaments. Two empirical correlations for the two breakup flow patterns were proposed, which illustrate the significant contribution of bubble retraction to the breakup degree.

show abstract

The dynamics of bubble breakup in heart-shaped microchannels: Effect of structure

Cited by 5 publications

References 35 publications

Reshoring Fine Chemical and Pharmaceutical Productions

Reshoring Fine Chemical and Pharmaceutical Productions

Dynamics of Bubble Breakup in Improved AFRs with a Sharp Corner Structure

Splitting behavior and breakup mechanism of bubbles in the split‐and‐recombine microchannel

Contact Info

Product

Resources

About