Abstract:This paper deals with the global dynamics for a tuberculosis transmission model with age‐structure and relapse. The time delay in the progression from the latent individuals to becoming the infectious individuals is also considered in our model. We perform some rigorous analyses for the model, including presenting an explicit formula for the basic reproduction number of the model, addressing the persistence of the solution semiflow and the existence of a global attractor. Based on these analyses, we establish … Show more
“…Remark Note that the bounded feasible region Ω defined in Cao et al 1 missed the boundedness of T . For completeness, here, we add it to the invariant set.…”
Section: Previous Resultsmentioning
confidence: 99%
“…Various interesting and important mathematical models were developed to describe the underlying transmission mechanisms of TB. In this paper, we revisit the following age‐structured TB transmission model proposed 1 where S ( t ), E ( t , a ), I ( t ), and T ( t ) are the numbers of susceptible, latent individuals with infection age a , infective individuals, and recovered individuals at time t , respectively. Here, all individuals have the same natural death rate d .…”
Section: Introductionmentioning
confidence: 99%
“…Remark It should be noted that Cao et al 1 omitted the expression of I ∗ . For completeness, here, we recompute the existence of the unique ESS in detail.…”
Section: Introductionmentioning
confidence: 99%
“…The authors provided the through analysis of system (); however, the global stability of ESS was unresolved in Cao et al 1 if ℜ 0 > 1. The aim of this paper is to show that the ESS is always global asymptotic stability (GAS) whenever it exists.…”
where the global asymptotic stability (GAS) of the endemic steady state (ESS) was unresolved when ℜ 0 > 1. We recompute the existence of ESS in detail, re-establish the GAS of the disease-free steady state (DFSS) in a simple and direct manner, and, furthermore, resolve the GAS of ESS, which was left as an open problem in the above paper. We adopt the method of Lyapunov functional with a key skill of selecting some novel appropriate kernel functions.
“…Remark Note that the bounded feasible region Ω defined in Cao et al 1 missed the boundedness of T . For completeness, here, we add it to the invariant set.…”
Section: Previous Resultsmentioning
confidence: 99%
“…Various interesting and important mathematical models were developed to describe the underlying transmission mechanisms of TB. In this paper, we revisit the following age‐structured TB transmission model proposed 1 where S ( t ), E ( t , a ), I ( t ), and T ( t ) are the numbers of susceptible, latent individuals with infection age a , infective individuals, and recovered individuals at time t , respectively. Here, all individuals have the same natural death rate d .…”
Section: Introductionmentioning
confidence: 99%
“…Remark It should be noted that Cao et al 1 omitted the expression of I ∗ . For completeness, here, we recompute the existence of the unique ESS in detail.…”
Section: Introductionmentioning
confidence: 99%
“…The authors provided the through analysis of system (); however, the global stability of ESS was unresolved in Cao et al 1 if ℜ 0 > 1. The aim of this paper is to show that the ESS is always global asymptotic stability (GAS) whenever it exists.…”
where the global asymptotic stability (GAS) of the endemic steady state (ESS) was unresolved when ℜ 0 > 1. We recompute the existence of ESS in detail, re-establish the GAS of the disease-free steady state (DFSS) in a simple and direct manner, and, furthermore, resolve the GAS of ESS, which was left as an open problem in the above paper. We adopt the method of Lyapunov functional with a key skill of selecting some novel appropriate kernel functions.
In this study, an SIRE epidemic model including infection age, relapse age, and effect of protection for susceptible in environmental virus infectious diseases is investigated. We use the function ffalse(Sfalse)$f(S)$ to represent the protection of susceptible so as to reduce the probability that susceptible are exposed to the polluted environment and become infected, and the function gfalse(Sfalse)$g(S)$ represents the protection of susceptible so as to reduce the probability that susceptible are directly contact with infected persons and become infected. We obtain threshold R0$R_{0}$ and the basic properties of solutions. Further, we see that when R0<1$R_{0}<1$ the disease‐free equilibrium exists and is unique and globally asymptotically stable, and when R0>1$R_{0}> 1$, besides the disease‐free equilibrium, the model has a unique endemic equilibrium that is locally asymptotically stable. Furthermore, we only obtained the system is uniformly persistence without the global asymptotical stability of endemic equilibrium when R0>1$R_0>1$. The numerical examples show that there exists a stable manifold of endemic equilibrium when R0>1$R_0>1$.
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