The duration of pregnancy in ecologically-challenged area. The effects of environmental pollution with aromatic hydrocarbons on the angiogenesis and elements of the mesenchymal tissue of the human placenta

Wierzba, Waldemar; Radowicki, Stanisław; Bojar, Iwona; Pinkas, Jarosław

doi:10.5603/gp.a2017.0035

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Wierzba, on the other hand, has shown that, the foetus is protected by activation of adaptation and compensation mechanisms that are manifested as active angiogenesis and formation of new blood vessels that provide proper nutrition and oxygen supply to the foetus and significantly greater development of mesenchymal cells compared to the control group [28].…”

Section: Discussionmentioning

confidence: 99%

Effects of environmental pollution with aromatic hydrocarbons on endocrine and metabolic functions of the human placenta

Wierzba

Radowicki

Bojar

et al. 2018

Ann Agric Environ Med.

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Section: Discussionmentioning

confidence: 99%

Effects of environmental pollution with aromatic hydrocarbons on endocrine and metabolic functions of the human placenta

Wierzba

Radowicki

Bojar

et al. 2018

Ann Agric Environ Med.

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“…demonstrated that the foetus is protected by activation of adaptation and compensation mechanisms that are manifested as active angiogenesis and formation of new blood vessels that provide proper nutrition and oxygen supply to the foetus and significantly greater development of mesenchymal cells compared to the control group [29].…”

Section: Resultsmentioning

confidence: 99%

Proliferation and apoptosis of human placental cells exposed to aromatic hydrocarbons

et al. 2017

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Objectives: The objective of this study is to assess the effect of elevated urinary levels of aromatic hydrocarbons (AH) on the proliferation and apoptosis of human placental trophoblast cells obtained in the course of normal pregnancy in an AH-polluted region. Material and methods:Tissue material was obtained for study purposes from 50 afterbirths from Płock as the study group and 50 afterbirths from Kutno as the control group. The extent and intensity of reactions were analyzed. The levels of phenol and 1-hydroxypyrene in the excreted urine of pregnant (in labor) patients were determined by gas chromatography and colorimetry. The proliferative activity of trophoblast cells was assessed using MPM-2 antibodies against phosphoprotein synthesized upon mitotic induction and Ki-67 antigen while the intensity of apoptosis in trophoblast cells was assessed using p53 and bcl-2 oncoproteins involved in apoptosis-regulating mechanisms. The immunohistochemical reactions were assessed for their extent and intensity. Results:The levels of phenol and 1-hydroxypyrene excreted in the urine were statistically significantly higher in patients from Płock region. The proliferative activity of trophoblast cells was statistically significantly higher in the study group (p < 0.05). The activity of oncoprotein bcl-2 was significantly higher in the study group while the activity of p53 was significantly higher in the control group.Pregnancy in an aromatic hydrocarbon-polluted environment has a significantly negative impact on placental tissue. Adaptation mechanisms are induced as manifested by increased proliferative activity within the trophoblast and extensive inhibition of apoptosis in the study group.

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Utilization of bark waste of Acacia mangium: The preparation of activated carbon and adsorption of phenolic wastewater

Zhang

Chen

et al. 2021

Industrial Crops and Products

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The duration of pregnancy in ecologically-challenged area. The effects of environmental pollution with aromatic hydrocarbons on the angiogenesis and elements of the mesenchymal tissue of the human placenta

Cited by 3 publications

References 9 publications

Effects of environmental pollution with aromatic hydrocarbons on endocrine and metabolic functions of the human placenta

Effects of environmental pollution with aromatic hydrocarbons on endocrine and metabolic functions of the human placenta

Proliferation and apoptosis of human placental cells exposed to aromatic hydrocarbons

Utilization of bark waste of Acacia mangium: The preparation of activated carbon and adsorption of phenolic wastewater

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