2009
DOI: 10.1590/s1516-44462009000400011
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The drug-naïve OCD patients imaging genetics, cognitive and treatment response study: methods and sample description

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Cited by 19 publications
(15 citation statements)
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References 28 publications
(24 reference statements)
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“…The present study focused on the most significant and nominally significant genes associated with OCD as inclusion criteria by cross-referencing these publications with GWAS and meta-analyzed genetic association (Azzam and Mathews, 2003;Lin, 2007;Pooley et al, 2007;Stewart et al, 2013aStewart et al, , 2013bTaylor, 2013;Walitza et al, 2014b). A publication by Hoexter et al (2009) was not included in the review because it did not include genetic association results in addition to their findings of single-photon emission computed tomography or magnetic resonance imaging in OCD. This particular publication describes the protocol of an ongoing study of treatment response to either a selective serotonin reuptake inhibitor (fluoxetine) or cognitive behavioral therapy compared with controls, in which the authors plan to combine findings generated from genetics (variable number of tandem repeats in the 3 0 -UTR of the dopamine transporter/SLC6A3), neuropsychology, structural magnetic resonance imaging, and molecular neuroimaging of the dopamine transporter (Hoexter et al, 2009).…”
Section: Resultsmentioning
confidence: 99%
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“…The present study focused on the most significant and nominally significant genes associated with OCD as inclusion criteria by cross-referencing these publications with GWAS and meta-analyzed genetic association (Azzam and Mathews, 2003;Lin, 2007;Pooley et al, 2007;Stewart et al, 2013aStewart et al, , 2013bTaylor, 2013;Walitza et al, 2014b). A publication by Hoexter et al (2009) was not included in the review because it did not include genetic association results in addition to their findings of single-photon emission computed tomography or magnetic resonance imaging in OCD. This particular publication describes the protocol of an ongoing study of treatment response to either a selective serotonin reuptake inhibitor (fluoxetine) or cognitive behavioral therapy compared with controls, in which the authors plan to combine findings generated from genetics (variable number of tandem repeats in the 3 0 -UTR of the dopamine transporter/SLC6A3), neuropsychology, structural magnetic resonance imaging, and molecular neuroimaging of the dopamine transporter (Hoexter et al, 2009).…”
Section: Resultsmentioning
confidence: 99%
“…A publication by Hoexter et al (2009) was not included in the review because it did not include genetic association results in addition to their findings of single-photon emission computed tomography or magnetic resonance imaging in OCD. This particular publication describes the protocol of an ongoing study of treatment response to either a selective serotonin reuptake inhibitor (fluoxetine) or cognitive behavioral therapy compared with controls, in which the authors plan to combine findings generated from genetics (variable number of tandem repeats in the 3 0 -UTR of the dopamine transporter/SLC6A3), neuropsychology, structural magnetic resonance imaging, and molecular neuroimaging of the dopamine transporter (Hoexter et al, 2009). Table 1 summarizes all imaging-genetic findings regarding genes associated with OCD.…”
Section: Resultsmentioning
confidence: 99%
“…This project was conducted in our outpatient OCD clinics at the University of São Paulo Medical School, Brazil (protocol, training, and reliability of instruments can be found elsewhere) (Hoexter et al, 2009;Miguel et al, 2008).…”
Section: Subjectsmentioning
confidence: 99%
“…From 623 patients referred to our OCD clinic from 2006 to 2008 (Hoexter et al, 2009), 254 were excluded in the telephone screening and 328 were excluded in the psychiatric medical assessment mainly for not being treatment naive (Supplementary Figure S1). In all, 41 OCD patients participated.…”
Section: Subjectsmentioning
confidence: 99%
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