The doppler method for measuring cardiac output in conscious rabbits: Validation studies, uses, and limitations

Hof, Robert P.; Hof, Akiko; StÜrm, Rolf P.

doi:10.1016/0160-5402(90)90011-9

Cited by 9 publications

(1 citation statement)

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“…18,19 Limitations of this study The measurement of cardiac output by the means of an ultrasonic Doppler probe positioned on the ascending aorta has been demonstrated to be as accurate as the thermodilution technique. [22][23][24] We used high pulse repetition frequency pulsed Doppler modules for blood flow measurement in small arteries, in order to avoid the aliasing phenomenon that could have resulted in unreadable graphs or false values. Nevertheless, although implanted Doppler probes are widely used for volume blood flow measurement in physiological studies, there are some causes of error.…”

Section: Effects Of Peep On Renal Artery Blood Flowmentioning

confidence: 99%

Regional blood flows are affected differently by PEEP when the abdomen is open or closed: An experimental rabbit model

et al. 2002

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Objective: The study of induced circulatory changes requires simultaneous assessment of multiple regional circulations because of interactions and compensatory mechanisms. Positive end expiratory pressure mechanical ventilation (PEEP) is known to cause marked, and potentially deleterious, cardiovascular changes. Our aim was to use a comprehensive approach to assess PEEP-induced circulatory changes in open vs closed abdomen animals. Material and methods:In the anesthetized rabbit, we used implantable Doppler micro-probes to measure blood flow simultaneously in the ascending aorta, inferior vena cava, portal vein, hepatic artery, common carotid artery, and renal artery. We studied spontaneously breathing animals (Group A), and open (Group B) and closed abdomen (Group C) animals mechanically ventilated at 0 (ZEEP) and 12 cm H 2 O PEEP.Results: In Group A, all biological and hemodynamic variables remained unchanged for three hours at the end of the surgical procedure. In Groups B and C, ZEEP produced no significant hemodynamic change. PEEP induced a decrease in carotid, hepatic, and renal artery blood flow in Groups B and C, a decrease in heart rate and mean arterial blood pressure in Group B, and a decrease in aorta blood flow in Group C.

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