The DNA damage response relies on the characteristics of ionizing particles in myogenic cells
Haser Hasan Sutcu,
Arthur Thomas--Joyeux,
Mikaël Cardot-Martin
et al.
Abstract:DNA integrity and stability are vital for proper cellular activity. Nevertheless, to treat cancer patients, DNA is the main target for inducing tumoral cell death. Nowadays, cancer treatment is improving by the development of new technologies, protocols and strategies. Amongst them, the introduction of charged particles as a form of radiotherapy is underway. However, tumor-neighboring healthy tissues are still exposed to ionizing radiations (IR) and subject to late side effects. Skeletal muscle is one of those… Show more
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