The diversity of clinicalMycobacterium abscessusisolates in morphology, glycopeptidolipids and infection rates in a macrophage model
Virginia Pichler,
Lara Dalkilic,
Ghazaleh Shoaib
et al.
Abstract:Mycobacterium abscessus (Mab) colonies adopt smooth (S) or rough (R) morphotypes, which are linked to the presence or absence of glycopeptidolipids (GPL), respectively. Though clinically relevant, the association between GPL levels, morphotype and pathogenesis are poorly understood. To investigate the degree of correlation between Mab morphology, GPL levels, and infectivity, we generated isolates from Mab-positive sputum samples from cystic fibrosis patients. Isolated strains were categorised based on their mo… Show more
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