The Disturbances of Magnesium in Patients With Thromboembolic Complications After a Cholecystectomy

Kopański, Z; Schlegel-Zawadzka, Małgorzata; Piekoszewski, Wojciech; Sadlik, Krystyna; Sibiga, W

doi:10.1016/s0049-3848(00)00278-4

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Calcium and magnesium concentrations were measured in serum, the Hp, and PFC using flame atomic absorption spectroscopy, as published previously (Kopanski et al 2000 ). The Hp and PFC were weighted (0.018–0.198 g) and digested in 1.5 ml of concentrated nitric acid (SupraPur—Merck).…”

Section: Methodsmentioning

confidence: 99%

Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats

et al. 2015

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Our previous study showed that dietary zinc restriction induces depression-like behavior with concomitant up-regulation of the N-methyl-d-aspartate receptor (NMDAR). Because metal ions, oxidative stress, and inflammation are involved in depression/NMDAR function, in the present study, bio-elements (zinc, copper, iron, magnesium, and calcium), oxidative (thiobarbituric acid-reactive substances; protein carbonyl content), and inflammatory (IL-1α, IL-1β) factors were measured in serum, hippocampus (Hp), and prefrontal cortex (PFC) of male Sprague–Dawley rats subjected to a zinc-adequate (ZnA) (50 mg Zn/kg) or a zinc-deficient (ZnD) (3 mg Zn/kg) diet for 4 or 6 weeks. Both periods of dietary zinc restriction reduced serum zinc and increased serum iron levels. At 4 weeks, lowered zinc level in the PFC and Hp as well as lowered iron level in the PFC of the ZnD rats was observed. At 6 weeks, however, iron level was increased in the PFC of these rats. Although at 6 weeks zinc level in the PFC did not differ between the ZnA and ZnD rats, extracellular zinc concentration after 100 mM KCl stimulation was reduced in the PFC of the ZnD rats and was accompanied by increased extracellular iron and glutamate levels (as measured by the in vivo microdialysis). The examined oxidative and inflammatory parameters were generally enhanced in the tissue of the ZnD animals. The obtained data suggest dynamic redistribution of bio-elements and enhancement of oxidative/inflammatory parameters after dietary zinc restriction, which may have a link with depression-like behavior/NMDAR function/neurodegeneration.

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Section: Methodsmentioning

confidence: 99%

Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats

et al. 2015

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“…Magnesium sulfate has been shown in in vivo experiments to reduce mortality in induced acute thromboembolismin mice [55]. It has been shown that after cholecystectomy, higher levels of magnesium were found in patients who did not develop thrombosis of the lower limbs compared to those who did [56]. The role of magnesium in preventing thromboembolic events in patients after gynecological surgery has not yet been explored, but perhaps would show similar results.…”

Section: Gynecological Surgerymentioning

confidence: 99%

Magnesium in Women’s Health and Gynecology

Tonick¹,

Muneyyirci-Delale²

2016

OJOG

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Magnesium is well known in the world of obstetrics for many important uses. It has been utilized in treating pre-eclampsia, eclampsia, and preventing preterm labor, though it has been found recently that prolonged magnesium administration in pregnant women may result in adverse outcomes to fetal bone metabolism, resulting in a new FDA warning [1]. Outside of obstetrics, magnesium is recommended for treating the arrhythmias torsades de pointes and rapid atrial fibrillation, treating severe acute asthma, improving migraine symptoms, and for treating dyspepsia and constipation [2]. Many women in our modern society are magnesium deficient due to low dietary intake, and low dietary magnesium intake resulting in hypomagnesaemia has recently been shown to have many deleterious effects. Magnesium's uses are wide-reaching, touching many areas of women's health and gynecology from pre-menstrual syndrome to menopause, PCOS to endometriosis, and beyond.

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The Disturbances of Magnesium in Patients With Thromboembolic Complications After a Cholecystectomy

Cited by 2 publications

References 7 publications

Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats

Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats

Magnesium in Women’s Health and Gynecology

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