The distribution of trace elements in normal human liver determined by semi-automated radiochemical neutron activation analysis

Antimony in lung, liver and kidney tissue from deceased smelter workers.

“…The antimony values of the lung, liver, and kidney tissues of the reference group agree well with the normal values that have been reported up to now (17,19). In this study, as in other studies, it was found that lung contains more antimony than liver and kidney tissues (13,19,31).…”

International review of environmental specimen banking

“…For the majority of the elements, the standard deviation for a set of 10 1-g test portions of a single liver was observed to be smaller than 5 percent and less than 2 percent for several of the essential trace elements for which large differences (e.g., a factor for 1000) in 1-g test portions were reported previously [23].…”

“…Despite the macroscopic homogeneous appearance of human liver, large inhomogeneities within a single liver have been reported when using one gram analytical test portions [23]. To evaluate storage conditions and to completely characterize the bulk liver sample, analytical results from different subsamples of the same liver must be compared.…”

Toxicological Profile for Zinc

“…Analysis of fecal samples obtained 3 and 6 days after the administration of zinc-65 isotope in food showed that between 45 and 75% of zinc isotope was absorbed (Johnson 1982 Multi-elemental analysis has been used to detect zinc and other trace metals in biological fluids and tissues. For determination of metallic constituents in biological samples, such as liver, samples were digested with mixtures of different acids, volatile elements were distilled by selective distillation, and a cleanup step was performed using ion exchange chromatography prior to assay by neutron activation analysis (NAA) (Lievens et al 1977). Recovery (98%) and precision (<10% CV) were excellent.…”