The distribution of oral mucosal pH values in healthy saliva secretors

Aframian, Doron J.; Davidowitz, T; Benoliel, Raphael

doi:10.1111/j.1601-0825.2005.01217.x

Cited by 182 publications

(123 citation statements)

References 19 publications

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“…Although the positioning of the tape on the back of the tongue [16] can represent a study limitation, as the values measured at this location are higher than those found if the measurement was performed in the saliva [17], the results of this study confirm the significant reduction in the pH of the oral environment after ingestion of this soft drink, which may lead to losses in the mineral balance of the dental structure immediately after consumption.…”

Section: Discussionsupporting

confidence: 72%

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Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Almenara

Rebouças

Cavalli

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

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Objective: To evaluate the influence of Coca-Cola ® consumption on the salivary pH of 12-year old children. Material and Methods: The convenience sample was composed of forty-five 12-year old students of both genders from public schools of Itatiba, state of São Paulo, Brazil. Salivary pH was measured with pH colorimetric tape indicator (Merck). The reading of the colorimetric method was made by an experienced evaluator under uniform lighting conditions. The colorimetric tape was positioned in the back of the student's tongue, which remained with the mouth shut for 30 Seconds. For control, the first measurement (T0) was performed before the intake of the soft drink (baseline pH). Subsequently, students were instructed to slowly drink 100 ml of Coca-Cola ® using a plastic disposable cup. Immediately after ingestion, the pH was measured again with the colorimetric tape (t1). The oral pH values were also measured 5 minutes (t2), 10 minutes (t3) and 15 minutes (t4) after the soft drink intake, keeping the tape positioning always the same in all measurements. The statistical SAS software was used for data analysis. Comparisons of oral pH values at different times were performed by the Tukey-Kramer test adopting 5% significance level. Results: Immediately after soft drink intake, the salivary pH significantly decreased (pH = 6.26) (p <0.05) compared to baseline (pH = 7.23) (p <0.05). Fifteen minutes after ingestion, although an increase in the pH was observed (pH = 6.64), it had not yet returned to baseline (T0) (p <0.05). Conclusion: Coca-Cola ® intake caused a significant reduction in salivary pH, without, however, reaching critical pH for enamel demineralization.

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Section: Discussionsupporting

confidence: 72%

“…Based on predetermined exclusion criteria (physical limitation that prevented the examination, medication user and baseline salivary pH), seven children were excluded by presenting initial salivary pH (detected only after the first measurement) below 6.8 [17], resulting a total sample of 45 students (n = 45), 26 females and 19 males.…”

Section: Thismentioning

confidence: 99%

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Almenara

Rebouças

Cavalli

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

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“…(i) We assume that the combination of neutral pH, hemin, and no CO 2 , which gives the shortest branching time (Figures 2 and 4), is a suitable model of the oral cavity [20], where bleeding occurs frequently as a result of a wide spectrum of pathological conditions [3,58,59]. It is important to note that hemin is released by oxidized ferric (Fe 3+ ) hemoglobin in the human body [60], and hemin has been demonstrated to initiate the Y → H morphological transition of C. albicans in vitro [13,14], which is likely to facilitate the superficial invasion of the oral mucosa by C. albicans in vivo [50,61,62].…”

Section: Discussionmentioning

confidence: 99%

“…albicans is able to colonize mucosa as a pathogenic fungus in a wide range of pH and CO 2 values [16,19]. For example, the mucosal pH in the oral cavity varies between 6.28 ± 0.36 (buccal mucosa) and 7.34 ± 0.38 (palate) with a mean value of 6.78 [20]. Meanwhile, the gastrointestinal tract shows wide differences in pH considering values reported for the stomach (extremely acidic like pH 2.0) and the intestine (pH~6.0-8.0) [16,21,22].…”

Section: Introductionmentioning

confidence: 99%

Effects of hemin, CO2, and pH on the branching of Candida albicans filamentous forms

Jakab

Antal

Emri

et al. 2016

Acta Microbiologica et Immunologica Hungarica

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Morphological transitions of wild-type and oxidative stress-tolerant Candida albicans strains were followed in the RPMI-FBS culture medium at pH values and CO 2 levels characteristic for the anatomical niches inhabited by this opportunistic human pathogen fungus, including the oral cavity as well as the intestinal and vaginal lumens. Selected cultures were also supplemented with hemin modeling bleedings. Germination as well as elongation and branching of hyphae were monitored in the cultures using time-lapse video microscopy. Unexpectedly, branching time, which is defined as the time taken until the first branch of hypha emerges for the first time after germination, correlated well with alterations in the environmental conditions meanwhile no such correlations were found for germination time (time lasted until the *Corresponding author; E-mail: pocsi.istvan@science.unideb.hu : 10.1556/030.63.2016.023 First published online December 8, 2016 1217-8950/$ 20.00 © 2016 Akadémiai Kiadó, Budapest appearance of the germination tube). Based on these observations, hypotheses were set up to estimate the significance of branching time in the pathogenesis of both superficial and systemic candidiases.Acta Microbiologica et Immunologica Hungarica 63 (4), pp. 387-403 (2016) DOI

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“…Kod nižih vrijednosti pH, primjerice kod pH = 6,9 (pH u mišićnim stanicama) 27 i 6,3 (pH sluznice usne šupljine), 28 kao u prethodnom slučaju, vrsta koja dominira je SO 4 2− (više od 99,99 %), dok je udjel HSO 4 − vrlo malen i on iznosi približno 0,001 % za pH = 6,9, a oko 0,005 % za pH = 6,3.…”

unclassified

Anorganski spojevi sumpora u ljudskom tijelu. I. Okso-spojevi.

Stanković¹,

Kiralj²

2017

Kem. Ind.

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Ovo djelo je dano na korištenje pod Creative Commons Attribution 4.0International License Veleučilište u Bjelovaru, Trg Eugena Kvaternika 4, 43 000 Bjelovar, Hrvatska Sažetak Sumpor je nakon kalcija i fosfora najzastupljeniji element u ljudskom tijelu, gdje se nalazi u mnogobrojnim anorganskim i organskim spojevima, a u vrlo malim količinama i u elementarnom stanju. U ovom pregledu prikazani su anorganski spojevi sumpora iz klase endogenih okso-spojeva u ljudskom organizmu, koji ponajprije nastaju enzimskim i neenzimskim biosintetskim putevima u stanicama ili izvanstaničnom prostoru. Opisani su sulfati, tiosulfati, μ-disulfido-bis(trioksosulfati)(2-) (tetrationati), sulfiti, hidrogensulfiti, sulfonati i disulfiti najzastupljenijih metala u organizmu (Na, Ca 2+ i Mg 2+ ) i sumporov dioksid. Anioni i SO 2 jesu endogene neradikalske sumporove vrste koje se nalaze u znatnim koncentracijama u tjelesnim tekućinama, gdje imaju zasebne fiziološke, patološke, metaboličke, detoksikacijske i druge uloge. Međusobno su povezani metaboličkim putevima sumporovih spojeva. Dok je sulfatni ion redovit sastojak elektrolita i izvor sumpora, tiosulfatni ion ima brojne zaštitne funkcije i važan je metabolit, a anioni nastali reakcijom SO 2 i vode također su važni metabolički među-produkti. Novijim istraživanjima prepoznate su uloge sumporova dioksida kao nove signalne molekule i aniona μ-disulfido-bis(trioksosulfata)(2-), kao metabolita koji se stvara tijekom upale crijeva. Istraživanja o opisanoj klasi sumporovih spojeva i njihovoj važnosti za ljudski organizam očito nisu završena i mogu još donijeti važne i neočekivane spoznaje.

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The distribution of oral mucosal pH values in healthy saliva secretors

Abstract: This method is easy and relatively quick to manipulate, and may offer many diagnostic possibilities for oral related diseases and disorders such as oral malodour, mouth breathing, dysgeusia, acidic diet consumption and gastrointestinal disorders affecting the mouth.

Cited by 182 publications

References 19 publications

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Effects of hemin, CO2, and pH on the branching of Candida albicans filamentous forms

Anorganski spojevi sumpora u ljudskom tijelu. I. Okso-spojevi.

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