1969
DOI: 10.1001/archsurg.1969.01340090123023
|View full text |Cite
|
Sign up to set email alerts
|

The Dissemination of Subcutaneously Inoculated Tumor Cell Suspensions

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
2
0
1

Year Published

2001
2001
2006
2006

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 13 publications
(3 citation statements)
references
References 5 publications
0
2
0
1
Order By: Relevance
“…In this context it is interesting to mention that, as shown in animal models as early as the 1970s [34], the presence of lymph node metastases does not necessarily correlate with the presence of occult metastatic cells in bone marrow. Numerous studies so far have demonstrated that the presence of immunocytochemically identifiable lymph node [1].…”
Section: Prognostic Relevance Of Bone Marrow Micrometastasesmentioning
confidence: 99%
“…In this context it is interesting to mention that, as shown in animal models as early as the 1970s [34], the presence of lymph node metastases does not necessarily correlate with the presence of occult metastatic cells in bone marrow. Numerous studies so far have demonstrated that the presence of immunocytochemically identifiable lymph node [1].…”
Section: Prognostic Relevance Of Bone Marrow Micrometastasesmentioning
confidence: 99%
“…In breast cancer, tumor cell dissemination to the regional lymph nodes occurs through the lymphatic vasculature 6 but may also occur directly through the hematogenous route; it seems that different biologic mechanisms are required for the lymphatic or hematogenous dissemination of tumor cells. 7,8 The detection of occult tumor cells in the bone marrow or peripheral blood of patients with earlystage breast cancer has been shown to be an independent predictive and prognostic factor for early disease recurrence and decreased overall survival. [9][10][11][12][13] Recently, Braun et al 4 reported that the immunohistochemical detection of bone marrow-disseminated tumor cells (DTCs) in 4,703 patients with operable breast cancer was an independent prognostic parameter for early relapse and death during the first 5 years of follow-up.…”
Section: Introductionmentioning
confidence: 99%
“…Auch der Lymphknotenstatus ist in experimentellen [22] und klinischen Studien [7,12,23,26] sowie lokalen Krebsregistern [20] nicht direkt mit einer hämatogenen Disseminierung von Tumorzellen zu korrelieren. Dies liefert die Motivation nach "neuen" prognostischen bzw.…”
Section: A Fragen Die Durch Laufende Studien Noch Nicht Beantwortet unclassified