The Discrete-Continuous, Global Optimisation of an Axial Flow Blood Pump

Tesch, K.; Kaczorowska-Ditrich, Katarzyna

doi:10.1007/s10494-019-00100-5

Cited by 7 publications

(9 citation statements)

References 20 publications

(28 reference statements)

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“…In this study, only seven design variables were considered to optimize the design. In recent literature, Tesch et al 225 used a fully automated iterative enhancement method for the global optimization of an axial blood pump. This optimization process was based on a modified evolutionary algorithm coupled with the CFD technique.…”

Section: Optimizationmentioning

confidence: 99%

Analysis of rotary ventricular assist devices using CFD technique—A Review

Shukla

Mishra

Tewari

2022

Proceedings of the Institution of Mechanical Engineers, Part E:

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With the increasing focus on reducing deaths because of heart ailments, considerable emphasis has been directed toward the development of ventricular assist devices (VADs) that work on the principle of mechanical pumps for supporting an infirm heart. The VADs are used primarily to assist the left ventricle, but their use has been extended for supporting the right ventricle as well as for supporting both ventricles simultaneously. In this connection, computational fluid dynamics (CFD) has evolved as an efficient technique for the design, development, evaluation, and optimization of VADs, enabling the prediction of operational characteristics of VADs as well as detailed global and local flow characteristics for an extensive set of working environments even before the manufacture and use of the actual device. CFD techniques yield valuable insight into the VADs’ effectiveness that enhances its operational behavior and decreases the risk associated with the use of the device, and at the same time decreases the manufacturing lead time and costs associated with the device. CFD has been quite beneficially used for the performance evaluation of VADs, but it still needs further development as hemolysis and thrombosis models cannot be easily integrated with the flow simulations. This review article presents abrief introduction to rotary VADs with a primary focus on the current status of CFD analysis of axial VADs, which provide the most suitable methods for computational design and optimization of VADs. It also identifies critical knowledge gaps and outlines the hematological models and the difficulties encountered in integrating them into CFD. Finally, future work based on the current scenario is also included.

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Section: Optimizationmentioning

confidence: 99%

Analysis of rotary ventricular assist devices using CFD technique—A Review

Shukla

Mishra

Tewari

2022

Proceedings of the Institution of Mechanical Engineers, Part E:

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“…On the other hand, continuous flow devices are smaller, less noisy, and permit patient mobility. These pumps can be divided into axial [32,33] and centrifugal, where axial pumps are much smaller. In order to achieve the required pressure increments, axial pumps require significant angular velocities [34], which leads to unfavorable phenomena, i.e., thrombosis (blood clot formation at the bloodpump contact surface) [2,35] and hemolysis [36,37] phenomena.…”

Section: Introductionmentioning

confidence: 99%

Innovative Implantable Left Ventricular Assist Device—Performance under Various Resistances and Operating Frequency Conditions

et al. 2023

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This paper presents the operation of an innovative left ventricular assist device under various resistances and operating frequencies. The operating principle of the device is based on pulsatile blood flow, which is forced by a suction–discharge device pumping helium into a set of intra-cardiac balloons. In this way, the ejection fraction of the left ventricle is increased, and the mitral valve is additionally occluded. What is more, the suction–discharge device is part of a portable pumping system that is synchronized with the heart cycle by monitoring the ECG signal. The device is implanted in a minimally invasive manner and is suitable for patients with stage D heart failure accompanied with residual mitral regurgitation. A model of the heart was built on the basis of a realistically reconstructed heart geometry and is part of an overall test stand that allows for realistic conditions in the heart of patients with end-stage heart failure to be reproduced. In the following sections, example measurements of the pressures in the heart chambers and balloons are shown, demonstrating that the device works correctly at least on a laboratory scale. The entire device, including the pumping system, is portable and powered by a set of lithium-ion batteries. From the measurements, it was observed, for example, that the flow rate varies with the frequency of the portable external balloon pumping system, up to 2.5 kg/min for 100 cycles/min at low flow resistance. As the flow resistance of the hydraulic system increases, the pressure in the heart chamber and aorta increases while the flow rate decreases.

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“…Although studies have been conducted on these effects of impeller sidewall gaps, there is little work in the literature on the optimization of blood pumps. 21–24 In those few published studies, an improved version of the investigated pump is presented instead of the optimized version with heuristic or metaheuristic algorithms. 25,26 Zhu et al 21 presented a study using 14 variable points to optimize the camber line of the diffuser blade.…”

Section: Introductionmentioning

confidence: 99%

“…Ghadimi et al 23 studied the use of a genetic algorithm model, introducing an innovate simultaneous optimization of the impeller and the volute. Tesch and Kaczorowska-Ditrich 24 investigated wall shear stresses related to angular velocities in axial flow blood pumps via the differential evolution method.…”

Section: Introductionmentioning

confidence: 99%

Heuristic optimization of impeller sidewall gaps-based on the bees algorithm for a centrifugal blood pump by CFD

et al. 2021

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Optimization studies on blood pumps that require complex designs are gradually increasing in number. The essential design criteria of centrifugal blood pump are minimum shear stress with maximal efficiency. The geometry design of impeller sidewall gaps (blade tip clearance, axial gap, radial gap) is highly effective with regard to these two criteria. Therefore, unlike methods such as trial and error, the optimal dimensions of these gaps should be adjusted via a heuristic method, giving more effective results. In this study, the optimal gaps that can ensure these two design criteria with The Bees Algorithm (BA), which is a population-based heuristic method, are investigated. Firstly, a Computational Fluid Dynamics (CFD) analysis of sample pump models, which are selected according to the orthogonal array and pre-designed with different gaps, are performed. The dimensions of the gaps are optimized through this mathematical model. The simulation results for the improved pump model are nearly identical to those predicted by the BA. The improved pump model, as designed with the optimal gap dimensions so obtained, is able to meet the design criteria better than all existing sample pumps. Thanks to the optimal gap dimensions, it has been observed that compared to average values, it has provided a 42% reduction in aWSS and a 20% increase in efficiency. Moreover, original an approach to the design of impeller sidewall gaps was developed. The results show that computational costs have been significantly reduced by using the BA in blood pump geometry design.

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The Discrete-Continuous, Global Optimisation of an Axial Flow Blood Pump

Cited by 7 publications

References 20 publications

Analysis of rotary ventricular assist devices using CFD technique—A Review

Analysis of rotary ventricular assist devices using CFD technique—A Review

Innovative Implantable Left Ventricular Assist Device—Performance under Various Resistances and Operating Frequency Conditions

Heuristic optimization of impeller sidewall gaps-based on the bees algorithm for a centrifugal blood pump by CFD

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