The Discharging Ears In Adults In Ibadan, Nigeria Causative Agents And Antimicrobial Sensitivity Pattern

Oni, A.A.; Nwaorgu, O G B; Bakare, Rasheed; Ogunkunle, Morenike Oyewumi; Toki, R.A.

doi:10.4314/ajcem.v3i1.7341

Cited by 16 publications

(18 citation statements)

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“…We noticed that, among cephalosporin, a high resistance rate was exhibited against cefepime and cefotriaxone, which was consistent with other reports [20,21,30]. In contrast, earlier studies have reported cefepime to be the most effective antimicrobial agent against P. aeruginosa [31,[32][33]. However, this contradiction may be due to the continuous evolution of MDR strains worldwide.…”

Section: Discussionsupporting

confidence: 46%

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Helal¹,

Khan²

2015

Am. J. Biomed. Sci.

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One of the serious and growing challenges for infection control programs worldwide is hospital acquired infections. Pseudomonas aeruginosa is considered the most common cause of hospital acquired Gramnegative infections. Intensive exposure of hospital pathogens to biocides may result in the emergence of resistance not only to the biocides, but possibly to antibiotics as well. Thus, the current study was done to investigate the prevalence of qacE∆1 and qacE genes and their correlation to antibiotics and biocides resistance in Pseudomonas aeruginosa isolated in Egypt. The antimicrobial activity of six biocides against drug sensitive and multi-drug resistant Pseudomonas aeruginosa was evaluated. Phenol and formalin displayed a higher antimicrobial activity compared to other biocides tested. Minimum inhibitory concentration (MIC) values of chlorine releasing agents were higher than the dilution prescribed by their manufactures. The qacE∆1 gene was identified in 57.8% of multidrug resistant isolates and 21.4% in susceptible strains, While, qacE gene was only detected among multi-drug resistant Pseudomonas aeruginosa. This study reported a correlation between qacE∆1 and multidrug resistance Pseudomonas aeruginosa, while there was no correlation between the presence of qac genes and increased MIC values to biocides. The effectiveness of biocides is very important to control microbial population and prevent the transmission of infections in hospitals. In conclusion we highlight the need for health care facilities to assess the antimicrobial effectiveness of biocides periodically.

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Section: Discussionsupporting

confidence: 46%

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Helal¹,

Khan²

2015

Am. J. Biomed. Sci.

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“…S. aureus is an opportunistic pathogens and a normal flora of skin, but when it gains entrance into the human body it causes infection to tissues and mucous membranes (Ekpo et al, 2007). This is in line with the work of Oyeleke (2009) and Oni et al (2002) who also reported the Staphylococcus epididermis, Staphylococcus aureus, Pseudomonas aeruginosa and other bacteria in adult patients of otitis media. This study reveals that bacteria causing otitis media has prevalence among the male patients at the in the two primary schools sampled in Ebonyi State, Nigeria.…”

Section: Discussionsupporting

confidence: 92%

“…Staphylococcus aureus was fully susceptible to gentamycin, erythromycin, ciprofloxacin, clindamycin, cotrimoxazole, ceftriaxone, augmentin and resistant to ampicilin, ofloxacin, Cephaplexin, also Staphylococcus epididermidis showed similar antibiogram profile when compared to Staphylococcus aureus, while Pseudomas aeruginosa was sensitive to ofloxacine, ceftriaxone and cotrimaxole and persistent to other antibiotics used, the disc diffusion method for sensitivity pattern was used. Contrarily, the resistance of these organisms was at variance with the result of Ogisi et al (1978) and Keith et al (1978) Oni et al (2002) who reported that these organisms were moderately susceptible to commonly used antibiotics.…”

Section: Discussionmentioning

confidence: 69%

Prevalence, Antibiogram of Bacterial Pathogens Associated with Otitis Media among Primary School Children in Ebonyi State

Alo¹

2012

IOSJPBS

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“…Twelve (85.7%) were positive for pathogens (monomicrobial in 11 and polymicrobial in 1). Staphylococcus aureus (28.6%), Pseudomonas aeruginosa (14.3%), Pseudomonas spp (7.1%), S. pneumoniae (7.1%), S. pyogenes (7.1%), Escherichia coli (7.1%), Klebsiella spp Table 1 Types of discharging ears and ear lesion [4][5][6] Also, in the tropics, empiric treatment is employed for most cases seen by general practitioners and nonotologists. This has given rise to the misuse of antimicrobial agents with the emergence of multiple antibiotic-resistant pathogens.…”

Section: Resultsmentioning

confidence: 99%

Clinical and microbiological profiles of ear infections in Osogbo, Nigeria

et al. 2006

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Despite the fact that discharging ears (DE) are one of the most common presentations to ear, nose and throat (ENT) clinics in the tropics, few reports have documented the aetiologic agents involved. The pathogenesis is therefore not fully understood and treatment remains controversial. We present in this report the microbiological characteristics of DE over a 3-year-period at the ENT clinic of Ladoke Akintola University Teaching Hospital, Osogbo, Southwest Nigeria.

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The Discharging Ears In Adults In Ibadan, Nigeria Causative Agents And Antimicrobial Sensitivity Pattern

Cited by 16 publications

References 0 publications

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Prevalence, Antibiogram of Bacterial Pathogens Associated with Otitis Media among Primary School Children in Ebonyi State

Clinical and microbiological profiles of ear infections in Osogbo, Nigeria

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