The dioxasilepanyl group as a versatile organometallic unit: studies on stability, reactivity, and utility

Abstract

Organic synthesis is orchestrated based on precise choices of functional groups and reactions employed. In a multistep synthesis, an ideal functional group should be orthogonal to various reaction conditions and...

Three-Component Carbosilylation of Alkenes by Merging Iron and Visible-Light Photocatalysis

“…After that, the Kambe group introduced titanocene-catalyzed carbosilylation of alkenes and dienes employing the Grignard reagent . A number of great efforts have been made by Engle, Li, and others in the carbosilylation of alkene using Pd and Fe catalysis. ,, In recent years, silicon-containing compound synthesis through silyl radical generation has become an interesting topic in this field. , In this context, photocatalytic carbosilylation of olefins through silyl radical formation has attracted a lot of attention . In spite of the developments in difunctionalization of alkenes, carbosilylation remains less explored …”

Synthesis of unsymmetrical dialkoxydiarylsilanes and diarylsilanediols from tetraalkoxysilane having a dioxasilepane unit

“…Thus, we considered the use of a seven-membered dialkoxysilyl moiety, the dioxasilepanyl group to circumvent this drawback. 17 This functional moiety was designed to provide both kinetic and thermodynamic stability to the alkoxysilyl moiety, allowing it to survive the reaction even when using butyllithium or LiAlH 4 (Fig. 1E).…”

“…In essence, the combination of the 7-membered ring structure and the trifluoroethoxy group successfully controlled the single substitution reaction. Of note, this seven-membered moiety helps to improve the stability of alkoxysilanes, 17 which are normally labile during chromatography and on contact with air and water. It is interesting to note that the substrate with the cyclic 1,3-propanediol diether ( 1-PDO ) only led to the selective formation of disubstituted diarylsilane 3aa .…”