The Differing Adipocyte Morphologies of Deep versus Superficial Midfacial Fat Compartments

Abstract

The significantly smaller adipocyte size in deep medial cheek fat relative to nasolabial fat in elderly subjects supports the theory that deep and superficial facial fat pads are morphologically different. Future investigation of the metabolic and structural properties of these fat compartments will help us understand the different patterns of volumetric facial aging.

Midfacial rejuvenation by hyaluronic acid fillers and subcutaneous adipose tissue – A new concept

“…The profound knowledge of midfacial anatomy represents the basis for a successful filler placement and helps to prevent unwanted adverse effects [4][5][6].…”

Lift-and-Fill Face Lift

“…With recent knowledge of the difference in deflation magnitude between the deep and superficial fat compartments, volume compensation is now mandatory. 18 The deep malar compartment has smaller fat lobule size and deflates at an accelerated rate. 18 This is the critical and first compartment to be filled.…”

“…18 The deep malar compartment has smaller fat lobule size and deflates at an accelerated rate. 18 This is the critical and first compartment to be filled. The submalar point in our study (point B) as well as the malar apex represent this deep compartment.…”

“…[1][2][3][4][5][6][7][9][10][11][12][13][14][16][17][18][19] However, the importance of varying specific SMAS vectors, depth/extent of dissection, amount of tissue mobilization, and other factors continually changes and is debatable. The superiority of one specific method of tissue (SMAS) manipulation over another has not been clearly determined.…”

“…[10][11][12][13] In addition, numerous studies have revealed the significance of facial fat in facial aging and techniques to restore it. [14][15][16][17][18] Various techniques with respect to SMAS manipulation exist but, to date, a single technique has not been shown to be superior over another. The missing link in efficacy of our face-lift results is now centered on the concept of precise volume augmentation as a mandatory component of optimal "lifting."…”