The Different Facets of Anhedonia and Their Associations with Different Psychopathologies

Shankman, Stewart A.; Katz, Andrea C.; DeLizza, Alison A.; Sarapas, Casey; Gorka, Stephanie M.; Campbell, Miranda L.

doi:10.1007/978-94-017-8591-4_1

Cited by 50 publications

(59 citation statements)

References 105 publications

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“…The specific relationship between PA and depression symptom trajectory shape was also unexpected, such that high PA variability did not appear to protect against the experience of depression symptoms over time. Because anhedonia (i.e., inability to experience PA) is a core symptom of depression that is present in over 70% of cases (Shankman et al, 2014), this may constrain the predictive power of PA variability, whereas high levels of PA are more consistently linked to well-being (Diener, 2000;Kahneman et al, 1999). Despite our results, additional future work should test the possibility that more variable PA could still Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Although depression is also typically characterized by low levels of PA (i.e., anhedonia; 70% of cases; Shankman et al, 2014) and the presence of anhedonia increases risk for chronic depression over the long term (e.g., Moos & Cronkite, 1999), less effort has focused on understanding the role of PA dynamics in depression. Characterizations of PA dynamics in depression appear to be less consistent than those of NA dynamics and may show nonlinear relationships with depression severity (see Houben et al, 2015).…”

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confidence: 99%

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Daily Affective Dynamics Predict Depression Symptom Trajectories Among Adults with Major and Minor Depression

2020

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Affective dynamics have been increasingly recognized as important indicators of emotional health and well-being. Depression has been associated with altered affective dynamics, but little is known about how daily life affective dynamics predict depression's naturalistic course. We investigated positive and negative affective dynamics (e.g., inertia, variability, and instability) among adults with depressive disorders (N = 60) and healthy controls (N = 38) in both cross-sectional and prospective analyses predicting weekly depression symptoms over 6 months. Relative to controls, depressed individuals showed elevated daily negative affect (NA) and NA variability along with decreased positive affect (PA). However, groups did not significantly differ on other affective dynamic indices. Based on multivariate prospective analyses of depressed individuals (follow-up N = 36), higher daily NA and lower daily PA were independently associated with higher and average weekly depressive symptom severity over the subsequent 6 months. Exploratory analyses of depression symptom trajectory shape revealed that higher NA and PA variability, NA inertia, and NA instability all predicted an initial increase and eventual return to higher depression symptom levels over the 6-month follow-up period. Daily life affective dynamics may have utility for predicting the naturalistic course of depression, which may help guide interventions targeting affective dynamics in vulnerable individuals.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Daily Affective Dynamics Predict Depression Symptom Trajectories Among Adults with Major and Minor Depression

2020

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“…For example, it has long been recognized as a negative symptom of schizophrenia, and is increasingly appreciated to be an important component of posttraumatic stress disorder, eating disorders and substance use disorder. 34 Anhedonia and apathy are measured using either questionnaires filled by the patient or caregiver, or by a structured interview performed by the clinician (Box 1). The closeness of apathy and anhedonia as syndrome constructs is emphasized by the results of a few studies that have examined both in clinical populations.…”

Section: Definitionsmentioning

confidence: 99%

Neuroscience of apathy and anhedonia: a transdiagnostic approach

2018

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Apathy and anhedonia are common syndromes of motivation that are associated with a wide range of brain disorders and have no established therapies. Research using animal models suggests that a useful framework for understanding motivated behaviour lies in effort-based decision making for reward. The neurobiological mechanisms underpinning such decisions have now begun to be determined in individuals with apathy or anhedonia, providing an important foundation for developing new treatments. The findings suggest that there might be some shared mechanisms between both syndromes. A transdiagnostic approach that cuts across traditional disease boundaries provides a potentially useful means for understanding these conditions.

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“…More specifically, patients with schizophrenia appear to manifest the deficit in the anticipation of pleasure rather than in the consummation of pleasure (Gard et al, 2007;Li et al, 2015;Lui et al, 2015;Mote et al, 2014), suggesting an abnormality in processing forthcoming rewards. Shankman et al (2014) have proposed that anticipatory reward processing could be divided into reward processing in the proximal future and the distal future. This allows researchers to investigate whether the decreased anticipatory pleasure found in patients with schizophrenia is due more to alteration in processing of rewards in the proximal or distal future.…”

Section: Introductionmentioning

confidence: 99%

Delay discounting and affective priming in individuals with negative schizotypy

Cai

Weigl

Liu

et al. 2019

Schizophrenia Research

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Previous studies have demonstrated that patients with schizophrenia and individuals with schizotypy experience decreased anticipatory pleasure. However, it is unclear whether this decrease is contributed by altered reward processing at the proximal or distal future. In order to investigate the preference for receiving rewards in the proximal or distal future for individuals with schizophrenia spectrum disorders, individuals with either high or low levels of negative schizotypy performed a delay discounting task under positive, neutral and negative affective priming conditions. Compared with individuals with low levels of negative schizotypy, individuals with high levels of schizotypy exhibited increased delay discounting, preferring to choose immediate but smaller rewards instead of delayed but larger rewards across all three affective priming conditions. Negative affective priming elevated discounting for both groups compared with both the positive and neutral affective conditions. After dividing delayed temporal distance into the proximal and distal future, the results showed that individuals with high levels of negative schizotypy exhibited more preference for immediate but smaller rewards in the distal instead of proximal future compared with controls. Our results suggest that individuals with high levels of negative schizotypy have altered anticipatory reward processing, which is mainly attributed to alterations in representing rewards in the distal future. These findings extend the alterations in representing reward values from schizophrenia patients to schizotypal individuals, and suggest that diminished anticipatory pleasure in schizophrenia spectrum disorders may be due to changes in processing anticipatory rewards in the distal future.

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The Different Facets of Anhedonia and Their Associations with Different Psychopathologies

Cited by 50 publications

References 105 publications

Daily Affective Dynamics Predict Depression Symptom Trajectories Among Adults with Major and Minor Depression

Daily Affective Dynamics Predict Depression Symptom Trajectories Among Adults with Major and Minor Depression

Neuroscience of apathy and anhedonia: a transdiagnostic approach

Delay discounting and affective priming in individuals with negative schizotypy

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