The differences of metabolic syndrome in elderly subgroups: A special focus on young-old, old-old and oldest old

Chuang, Tsung-Ju; Huang, Chia‐Luen; Lee, Chien-Hsing; Hsieh, Chang‐Hsun; Hung, Yi‐Jen; Hung, Chi‐Feng; Liang, Yao-Jen; Chen, Yen‐Lin; Hsia, Te-Lin; Pei, Dee

doi:10.1016/s0168-8227(16)31074-9

Cited by 3 publications

(6 citation statements)

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“…Data were analyzed using SPSS version 19.0 for Windows (SPSS, Inc., Chicago, IL, USA). Participants were categorized into three groups: young-old (age = 65-74 years), old-old (age = 75-84 years), and oldest-old (age ≥ 85 years) in accordance with other studies of elderly patients in Taiwan [29,30]. To provide missing data from the SCNS-SF34, we input the mean value of other items in the domain [25].…”

Section: Discussionmentioning

confidence: 99%

Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan

et al. 2021

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Background Globally, different age groups in the elderly population have experienced major shifts over time. Human life expectancy doubled from the 19th to the twentieth century and has increased to 80 years in the twenty-first century. These conditions imply economic challenges and the increasing prevalence of certain health conditions. Old age is associated with increased care needs in various aspects of daily life. This study assessed the health care needs of elderly patients with lung, liver, and colorectal cancer in Taiwan and analyzed the factors underlying their needs. Methods This cross-sectional descriptive survey assessed 234 elderly patients with diagnosis of lung, liver, and colorectal cancer in Taiwan. We investigated their health care needs and daily living functions by using the Supportive Care Needs Survey and Karnofsky Performance Status, respectively. Results Patients required the most assistance in physical functioning and daily living. Patients aged ≥85 years required more care than those aged 65–74 years in terms of information access and sexuality needs. Patients with poor functional status required more care than those capable of undertaking normal activities. Patients diagnosed as having liver cancer required more care than those with lung or colorectal cancer. Patients with advanced cancer required more physical and daily care than those with early-stage cancer. Conclusions Patients’ health care needs differed with age, primary cancer site, and functional status. Patients aged ≥85 years and those with poor function, primary liver cancer, and advanced cancer had higher care needs.

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Section: Discussionmentioning

confidence: 99%

Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan

et al. 2021

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Section: Discussionmentioning

confidence: 99%

“…Age categorization utilized the schema borrowed from other literature focusing on the physiologic differences that occur with aging: Young-old encompassed those aged 65 to 74 years, middle-old comprised those with age 75 to 84, and old-old were the population with age ≥85. 17 Differences in dysphonia etiology or V-RQOL between these subgroups of age and/or gender were analyzed with Pearson’s chi-square, analysis of variance, or Student’s t tests. Logistic regression models were used to analyze predictors of dysphonia categorization.…”

Section: Methodsmentioning

confidence: 99%

“…For instance, physiological and psychological differences between the young-old (65-74 years), middle-old (75-84), and old-old (>85) have been reported, creating differences in how these groups experience such varied medical issues as sleep difficulties, orthopedic injury, metabolic syndrome, and kidney failure. [16][17][18][19][20][21][22] It would seem that similar psychological and physiological difference might create differences in how the young-old, middle-old, and old-old experience dysphonia as well-for instance, a 66-year-old with ongoing workplace voice use will be at risk for different voice disorders and may experience impact of dysphonia differently than a retired octogenarian. Despite these potential differences, there has been little work to establish the differences between these phases of aging as it relates to specific diagnosis or quality of life burden of dysphonia, and the literature concerning dysphonia in those age ≥65 has treated them as a uniform population.…”

Section: Introductionmentioning

confidence: 99%

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Geriatric Dysphonia: Characteristics of Diagnoses in Age-Based Cohorts in a Tertiary Voice Clinic

Applebaum

Harun

Davis

et al. 2019

Ann Otol Rhinol Laryngol

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Objective: An aging population has increased focus on geriatric otolaryngology. Those ≥65 years old are not a uniform population, however, and recent gerontology literature recognizes important physiologic differences between the young-old (ages 65-74 years), middle-old (75-84), and old-old (≥85). This study evaluates differences within these groups among dysphonia patients ≥65 years relative to diagnosis and voice-related quality of life (V-RQOL). Methods: Chart review of all new patients ≥65 years presenting to the Johns Hopkins Voice Center between April 2015 and March 2017 identified chief complaint, diagnosis, and self-reported voice handicap. Etiology of dysphonia diagnoses were classified. Diagnostic categories and V-RQOL were evaluated as functions of patient age and gender. Results: Of 839 new patients ≥65 years, 463 (55.2%) reported chief complaint of dysphonia, with the most common etiologies being vocal fold immobility (28.3%) and atrophy (21.6%). Younger cohorts were more likely to present with benign vocal fold lesion and vocal fold immobility, while older cohorts were more likely to present with atrophy ( P = .016). The odds of having a diagnosis of vocal fold atrophy increased 7% with each year of life (odds ratio = 1.07; 95% CI, 1.03-1.11). V-RQOL scores were similar across gender and age categorization. Conclusion: Dysphonia patients ≥65 years are not a uniform group, and important differences exist in terms of diagnosis as a function of age. Knowledge of these differences may inform further investigations in the growing field of geriatric otolaryngology.

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“…Several studies have highlighted that elderly cannot be considered as one homogeneous group but rather as a heterogeneous group with regard to pattern of diseases and pharmacological therapy. 11,12 Consequently, a chronological definition establishing three age groups of older people (65-75 years; 75-85 years; ≥ 85 years) has been proposed, 13 whereas in Japan the aging population is stratified in two groups, early-stage (65-75 years) and later-stage elderly (≥ 75 years). 14 A retrospective study from Japan specifically compared the characteristics of DILI across different age groups of older adults (< 65 years; 65-74 years; and ≥ 75 years), 14 yet the number of elderly patients was limited.…”

Section: Articlementioning

confidence: 99%

Clinical Characteristics and Outcome of Drug‐Induced Liver Injury in the Older Patients: From the Young‐Old to the Oldest‐Old

Weersink

Robles‐Díaz

Ortega‐Alonso

et al. 2020

Clin Pharma and Therapeutics

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Older patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought the distinctive characteristics of DILI in older patients across age groups. A total of 882 DILI patients included in the Spanish DILI Registry (33% ≥ 65 years) were categorized according to age: "young" (< 65 years); "young-old" (65-74 years); "middle-old" (75-84 years); and "oldest-old" (≥ 85 years). All elderly groups had an increasingly higher comorbidity burden (P < 0.001) and polypharmacy (P < 0.001). There was a relationship between jaundice and hospitalization (P < 0.001), and both were more prevalent in the older age groups, especially in the oldest-old (88% and 69%, respectively), and the DILI episode was more severe (P = 0.029). The proportion of females decreased across age groups from the young to the middle-old, yet in the oldest-old there was a distinct female predominance. Pattern of liver injury shifted towards cholestatic with increasing age among top culprit drugs amoxicillin-clavulanate, atorvastatin, levofloxacin, ibuprofen, and ticlopidine. The best cutoff point for increased odds of cholestatic DILI was 65 years. Older patients had increased non-liver-related mortality (P = 0.030) as shown by the predictive capacity of the Model for End-Stage Liver Disease score (odds ratio (OR) = 1.116; P < 0.001), and comorbidity burden (OR = 4.188; P = 0.001) in the 6-month mortality. Older patients with DILI exhibited an increasingly predominant cholestatic phenotype across a range of culprit drugs, other than amoxicillin-clavulanate, with increased non-liver-related mortality and require a different approach to predict outcome. The oldest DILI patients exhibited a particular phenotype with more severe DILI episodes and need to be considered when stratifying older DILI populations.

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The differences of metabolic syndrome in elderly subgroups: A special focus on young-old, old-old and oldest old

Cited by 3 publications

References 0 publications

Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan

Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan

Geriatric Dysphonia: Characteristics of Diagnoses in Age-Based Cohorts in a Tertiary Voice Clinic

Clinical Characteristics and Outcome of Drug‐Induced Liver Injury in the Older Patients: From the Young‐Old to the Oldest‐Old

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