The differences in measured prostate material properties between probing and unconfined compression testing methods

Johnson, Bernadette; Campbell, Scott; Campbell-Kyureghyan, Naira

doi:10.1016/j.medengphy.2020.03.006

Cited by 4 publications

(1 citation statement)

References 38 publications

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“…In the example shown, the maximum amplitude of particle displacement was 1 mm, at the contact surface between emitter and urethral wall. The maximum shear strain generated was 4.5%, which is within the linear elastic regime for most soft tissues, this is 5–10%, and is below the irreversible damage threshold [ 65 ]. The amplitude of the wave rapidly decreased due to attenuation.…”

Section: Discussionmentioning

confidence: 99%

Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures

Gómez

Rus

Saffari

2021

Sensors

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In this article, a wave propagation model is presented as the first step in the development of a new type of transluminal procedure for performing elastography. Elastography is a medical imaging modality for mapping the elastic properties of soft tissue. The wave propagation model is based on a Kelvin Voigt Fractional Derivative (KVFD) viscoelastic wave equation, and is numerically solved using a Finite Difference Time Domain (FDTD) method. Fractional rheological models, such as the KVFD, are particularly well suited to model the viscoelastic response of soft tissue in elastography. The transluminal procedure is based on the transmission and detection of shear waves through the luminal wall. Shear waves travelling through the tissue are perturbed after encountering areas of altered elasticity. These perturbations carry information of medical interest that can be extracted by solving the inverse problem. Scattering from prostate tumours is used as an example application to test the model. In silico results demonstrate that shear waves are satisfactorily transmitted through the luminal wall and that echoes, coming from reflected energy at the edges of an area of altered elasticity, which are feasibly detectable by using the transluminal approach. The model here presented provides a useful tool to establish the feasibility of transluminal procedures based on wave propagation and its interaction with the mechanical properties of the tissue outside the lumen.

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Section: Discussionmentioning

confidence: 99%

Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures

Gómez

Rus

Saffari

2021

Sensors

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Biomechanical properties of abdominal organs under tension with special reference to increasing strain rate

Johnson

Campbell

Campbell-Kyureghyan

2020

Journal of Biomechanics

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Characterizing the Material Properties of the Kidney and Liver in Unconfined Compression and Probing Protocols with Special Reference to Varying Strain Rate

2021

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The liver and kidneys are the most commonly injured organs due to traumatic impact forces applied to the abdomen and pose a challenge to physicians due to a hard-to-diagnose risk of internal bleeding. A better understanding of the mechanism of injury will improve diagnosis, treatment, forensics, and other fields. Finite element modelling is a tool that can aid in this understanding, but accurate material properties are required including the strain rate dependency and the feasibility of using animal tissue properties instead of human. The elastic modulus in a probing protocol and the elastic modulus, failure stress, and failure strain in a compression protocol were found for both liver and kidney tissue from human and porcine specimens at varying strain rates. Increases in the elastic modulus were seen for both the human kidney and liver, but only for the porcine kidney, when comparing the unconfined compression and probing protocols. A strain rate dependency was found for both the liver and kidney properties and was observed to have a larger saturation effect at higher rates for the failure stress than for the elastic modulus. Overall, the material properties of intact liver and kidney were characterized, and the strain rate dependency was numerically modelled. The study findings suggest that some kidney and liver material properties vary from human to porcine tissue. Therefore, it is not always appropriate to use material properties of porcine tissue in computational or physical models of the human liver and kidney.

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The differences in measured prostate material properties between probing and unconfined compression testing methods

Cited by 4 publications

References 38 publications

Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures

Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures

Biomechanical properties of abdominal organs under tension with special reference to increasing strain rate

Characterizing the Material Properties of the Kidney and Liver in Unconfined Compression and Probing Protocols with Special Reference to Varying Strain Rate

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