The differences in epidemiological and psychological features of globus symptoms between urban and rural Guangzhou, China

Tang, Bei; Wang, Xiaogu; Chen, Chaoda; Deng, Xuqun; Ouyang, Xinqiang; Jia, Lin; Gong, Jianan

doi:10.1097/md.0000000000012986

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…In a prospective evaluation of 104 patients with globus, as many as 35% had anxiety disorder, and 13% had depression; 18% had borderline anxiety, while 28% had borderline depression 40 . Anxiety and hypochondriasis scores are higher in globus patients compared to those without this symptom, 41 and in urban residents compared to rural residents 42 . Both anxiety and depression appear to be more prevalent in females 40 .…”

Section: Etiology Of Globusmentioning

confidence: 86%

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge

Zerbib

Rommel

Pandolfino

et al. 2020

Neurogastroenterology Motil

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Globus is a non‐painful sensation of a tightness or a lump/foreign body in the throat that is not associated with dysphagia and may actually improve during meals. While several otorhinolaryngologic, thyroid, and esophageal disorders have been linked to globus, cause‐and‐effect relationships are difficult to establish. Consequently, though part of the evaluation, objective otorhinolaryngologic and esophageal testing is often negative. The presence of alarm symptoms, particularly pain, weight loss, dysphagia, or odynophagia is indications for objective testing. A diagnosis of idiopathic globus requires exclusion of pharyngeal, laryngeal, and esophageal disorders with laryngoscopy, endoscopy, high‐resolution manometry, barium radiography, and/or ambulatory reflux monitoring. A trial of acid‐suppressive therapy may be reasonable in the absence of alarm symptoms, especially if concurrent reflux symptoms are identified. Ablation of heterotopic gastric mucosa in the proximal esophagus has been reported to improve globus symptoms. Beyond these specific approaches, further management of idiopathic globus consists of reassurance, neuromodulators, and complementary approaches. Globus has a benign course with no long‐term consequences, and the overall prognosis is good as the magnitude of symptoms may decline over time.

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Section: Etiology Of Globusmentioning

confidence: 86%

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge

Zerbib

Rommel

Pandolfino

et al. 2020

Neurogastroenterology Motil

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show abstract

“…Various biopsychosocial factors (figure 1) further modulate its function and are yet to be fully explored (figure 1). 91 113 129–133 The complex potential for interaction among these factors in the generation of UCTS is outlined in figure 2 and is reminiscent of those that characterise DGBI.…”

Section: Diagnostic and Clinical Classifications Of Uctsmentioning

confidence: 99%

Practical multidisciplinary framework for the assessment and management of patients with unexplained chronic aerodigestive symptoms

Quigley,

Mistry,

Vasant

et al. 2023

BMJ Open Gastroenterol

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ObjectivePatients experiencing unexplained chronic throat symptoms (UCTS) are frequently referred to gastroenterology and otolaryngology outpatient departments for investigation. Often despite extensive investigations, an identifiable structural abnormality to account for the symptoms is not found. The objective of this article is to provide a concise appraisal of the evidence-base for current approaches to the assessment and management of UCTS, their clinical outcomes, and related healthcare utilisation.DesignThis multidisciplinary review critically examines the current understanding of aetiological theories and pathophysiological drivers in UCTS and summarises the evidence base underpinning various diagnostic and management approaches.ResultsThe evidence gathered from the review suggests that single-specialty approaches to UCTS inadequately capture the substantial heterogeneity and pervasive overlaps among clinical features and biopsychosocial factors and suggests a more unified approach is needed.ConclusionDrawing on contemporary insights from the gastrointestinal literature for disorders of gut–brain interaction, this article proposes a refreshed interdisciplinary approach characterised by a positive diagnosis framework and patient-centred therapeutic model. The overarching aim of this approach is to improve patient outcomes and foster collaborative research efforts.

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Functional Disorders of the Larynx: Muscle Tension Dysphonia, Paradoxical Vocal Cord Dysfunction, and Globus Pharyngeus

McNeely

2023

Functional Illness of the Head and Neck

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The differences in epidemiological and psychological features of globus symptoms between urban and rural Guangzhou, China

Cited by 3 publications

References 18 publications

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge

Practical multidisciplinary framework for the assessment and management of patients with unexplained chronic aerodigestive symptoms

Functional Disorders of the Larynx: Muscle Tension Dysphonia, Paradoxical Vocal Cord Dysfunction, and Globus Pharyngeus

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