The difference of mild cognitive impairment in Parkinson's disease from amnestic mild cognitive impairment: Deeper power decrement and no phase-locking in visual event-related responses

Are there consistent abnormalities in event‐related EEG oscillations in patients with Alzheimer’s disease compared to other diseases belonging to dementia?

“…Notably, these effects were not demonstrated at the individual level. Furthermore, they may be disease unspecific as similar abnormalities were observed in PDMCI (Güntekin et al, 2020;Yener et al, 2019), PDD (Güntekin et al, 2020), LBD (Rosenblum et al, 2020), and major VCI patients (Lou et al, 2011;Wang et al, 2016;Xu et al, 2011Xu et al, , 2015. Keeping the above data in mind, the present Expert Panel recommends that eventrelated delta and theta power during oddball tasks may be used in future clinical trials carried out in ADMCI and ADD patients for analyses at the group level.…”

“…visual oddball task was lower in both ADMCI and PDMCI patients compared to CU adults. Furthermore, theta phaselocking was lower in PDMCI but not ADMCI patients when compared to controls (Yener et al, 2019). Rosenblum et al (2020) showed that event-related theta power and phase-locking during a visual (but not auditory) oddball task was lower in LBD patients than in CU participants.…”

“…In another study, Yener et al (2019) compared event-related delta power and phase-locking responses during a visual oddball task between ADMCI, PDMCI, and CU groups. Results showed reduced event-related delta power in the PDMCI group compared to the CU group and reduced delta phase locking in the PDMCI group compared to the ADMCI group (Yener et al, 2019). Furthermore, Rosenblum et al (2020) analyzed event-related power and phase-locking during visual and auditory oddball tasks in LBD and CU groups.…”

“…Furthermore, some markers of event-related theta responses (particularly event-related power) were lower in ADMCI and ADD patients compared to CU adults (Başar et al, 2010;Caravaglios et al, 2010;Güntekin et al, 2008;Tülay et al, 2020;Yener et al, 2007). However, these effects may be non-specific as similar changes were observed in PDMCI (Güntekin et al, 2020;Yener et al, 2019), PDD (Güntekin et al, 2020), LBD (Rosenblum et al, 2020), and major VCI patients (Lou et al, 2011;Wang et al, 2016;Xu et al, 2011Xu et al, , 2015. Future comprehensive EEG experiments are therefore needed to compare event-related delta and theta responses among patients with different dementias at different levels of cognitive deficits.…”

Alpha Power and Functional Connectivity in Cognitive Decline: A Systematic Review and Meta-Analysis

“…Whereas upper alpha power decreased (ERD) for cognitively healthy older adults, it increased (ERS) for people with aMCI. On the other hand, Sharma et al [74], (n = 15 dementia, 16 MCI, 13 OA), Kurt et al [122], (n = 22 aMCI, 21 OA), and Yener et al [123], (n = 18 aMCI, 18 OA); [124], (n = 30 aMCI, 28 OA) did not find significant differences between people with MCI and cognitively healthy older adults during tasks of attention. Sharma et al [74] did find a difference between people with MCI and people with dementia, but the direction of the difference was unclear, and dementia and MCI were not diagnosed according to widely accepted criteria.…”