The Diagnostic Value of the American College of Radiology Thyroid Imaging Reporting and Data System Classification and Shear-Wave Elastography for the Differentiation of Thyroid Nodules

Makal, Gül Bora; Aslan, Aydın

doi:10.1016/j.ultrasmedbio.2021.01.023

Cited by 11 publications

(11 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Das Hinzuziehen der standardisierten Sonografie mittels eines RSS zeigt in vielen, auch prospektiven Studien, dass die Kombination aus morphologischen Kriterien und Elastografie zu einer Verbesserung der diagnostischen Genauigkeit bei unklarem FNB-Ergebnis führt [36,47,48,55,64,65,66,67,68,69].…”

Section: Elastografie Bei Bethesda Iii/iv-schilddrüsenknotenunclassified

Elastografie von Schilddrüsenknoten

Petersen

Klemenz

Schenke

2023

Angewandte Nuklearmedizin

View full text Add to dashboard Cite

Zusammenfassung Hintergrund Die Elastografie ist eine bildgebende Methode, um die Elastizität von Gewebe zu untersuchen. Inzwischen wurden verschiedene Elastografie-Verfahren entwickelt, die nach der Art des angewandten Stimulus unterteilt werden. Prinzipiell ist zwischen der Strain-Elastografie (SE) und Scherwellen-Elastografie (SWE) zu unterscheiden. Beide Methoden bieten neben der konventionellen B-Mode-Sonografie eine weitere Möglichkeit zur Beurteilung von Schilddrüsenerkrankungen. Ziel der Arbeit Es soll ein Überblick über die Elastografie-Verfahren einschließlich der physikalischen Grundlagen vermittelt werden sowie ihre Bedeutung im Abklärungsalgorithmus von Schilddrüsenknoten. Material und Methoden Internationale Leitlinien sowie aktuelle Arbeiten zur Elastografie wurden selektiv recherchiert. Ergebnisse Die Elastografie liefert zusätzliche Informationen gegenüber der konventionellen B-Mode-Sonografie. Der wesentliche physikalische Mechanismus, dem der Gewebekontrast in allen Elastogrammen zugrunde liegt, ist die Änderung der Schersteifigkeit. Neben der qualitativen Erfassung der Elastizität in der SE ist mit der SWE eine Quantifizierung möglich. In der internationalen Literatur wurde die Elastografie als einzelne Methode oder im Vergleich bzw. in Kombination zur konventionellen B-Mode-Sonografie und insbesondere mit der Standardisierung mittels eines Risikostratifizierungssystems (RSS, TIRADS) analysiert. Die Ergebnisse zeigten sich durchaus kontrovers. Bei Knoten mit unklaren Befunden der Feinnadelbiopsie (Bethesda III/IV) führte die Kombination aus morphologischen Kriterien und Elastografie zu einer Verbesserung der diagnostischen Genauigkeit. Insbesondere der hohe negative prädiktive Wert weicher Knoten stellt einen relevanten Mehrwert dar. Diese Stärke der Methode kann bei der Abklärung von Knoten mit mittlerem Malignomrisiko oder von unklaren FNB-Ergebnissen eine wichtige Rolle spielen. Die Elastografie wurde bisher nur in das (überwiegend durch das EU-TIRADS abgelöste) French-TIRADS integriert. Obwohl das Verfahren im EU-TIRADS als Komplementärmethode Erwähnung findet, wurde eine Integration nicht beschrieben. Limitationen des Verfahrens sind idealisierte Grundannahmen, Hersteller- und Untersucherabhängigkeit sowie Artefakte. Schlussfolgerung Die Elastografie kann bei der Beurteilung von Schilddrüsenknoten die standardisierten Diagnostikverfahren sinnvoll ergänzen, insbesondere bei Knoten mit mittlerem Malignomrisiko und unklaren Ergebnissen in der Feinnadelpunktion.

show abstract

Section: Elastografie Bei Bethesda Iii/iv-schilddrüsenknotenunclassified

Elastografie von Schilddrüsenknoten

Petersen

Klemenz

Schenke

2023

Angewandte Nuklearmedizin

View full text Add to dashboard Cite

show abstract

“…SWE is a new ultrasonic examination method for differentiating benign and malignant thyroid nodules, which makes up for the deficiency of traditional compression elastography that is easily affected by human factors. 7 Its principle is to excite the tissue by emitting acoustic radiation pulses, continuously focus the tissue at different depths, cause "Mach cone" phenomenon, generate shear waves of sufficient strength, display the tissue elasticity in real time by color coding technology, and express it in Young's modulus (kPa) reflecting the absolute hardness of the tissue, which is objective, repeatable, and less affected by the operator. 22 In the risk assessment of thyroid nodules, it is generally believed that the hardness of thyroid malignant nodules is higher than that of benign nodules.…”

Section: Shear Wave Elastographymentioning

confidence: 99%

“…Multimodal ultrasound imaging has been the focus of ultrasound diagnosis of thyroid nodules in recent years, including the combined application of two or more methods in conventional ultrasound, ACR TI-RADS, shear wave elastography (SWE), super micro vascular imaging (SMI), contrast enhanced ultrasound (CEU), "firefly" imaging and artificial intelligence (AI), and so forth. [7][8][9][10] Imaging of thyroid TI-RADS 4 nodules by multimodal ultrasound can concentrate the advantages of various methods. It is expected to adjust the classification of nodules, improve the diagnostic accuracy of benign and malignant TI-RADS 4 nodules, and reduce the puncture rate and manual operation rate of thyroid TI-RADS 4 nodules to a certain extent.…”

mentioning

confidence: 99%

“…Although surgical resection and pathological examination are the gold standard for differentiating benign and malignant thyroid nodules, noninvasive diagnostic methods are more easily accepted by patients and can avoid unnecessary biopsy and surgery. Multimodal ultrasound imaging has been the focus of ultrasound diagnosis of thyroid nodules in recent years, including the combined application of two or more methods in conventional ultrasound, ACR TI‐RADS, shear wave elastography (SWE), super micro vascular imaging (SMI), contrast enhanced ultrasound (CEU), “firefly” imaging and artificial intelligence (AI), and so forth 7–10 . Imaging of thyroid TI‐RADS 4 nodules by multimodal ultrasound can concentrate the advantages of various methods.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Multimodal ultrasound imaging: A method to improve the accuracy of diagnosing thyroid TI‐RADS 4 nodules

Han

Huang

Wang

et al. 2022

J of Clinical Ultrasound

View full text Add to dashboard Cite

Thyroid nodule is a common and frequently occurring disease in the neck in recent years, and ultrasound has become the preferred imaging diagnosis method for thyroid nodule due to its advantages of noninvasive, nonradiation, real‐time, and repeatable. The thyroid imaging, reporting and data system (TI‐RADS) classification standard scores suspicious nodules that are difficult to determine benign and malignant as grade 4, and further pathological puncture is recommended clinically, which may lead to a large number of unnecessary biopsies and operations. Including conventional ultrasound, ACR TI‐RADS, shear wave elastography, super microvascular imaging, contrast enhanced ultrasound, “firefly,” artificial intelligence, and multimodal ultrasound imaging used in combination. In order to identify the most clinically significant malignant tumors when reducing invasive operations. This article reviews the application and research progress of multimodal ultrasound imaging in the diagnosis of TI‐RADS 4 thyroid nodules.

show abstract

“…In a study investigating the role of the American College of Radiology Thyroid Imaging Reporting and Data System Classification and SWE in differentiating the nature of nodules, it was observed that SWE was more diagnostically accurate in all nodule sizes. However, it was also found that the detection rate decreased as the nodule size increased ( 10 ).…”

Section: Introductionmentioning

confidence: 99%

Factors Affecting Thyroid Elastography in Healthy Children and Patients with Hashimoto’s Thyroiditis

Koca¹,

Seber²

2023

Jcrpe

View full text Add to dashboard Cite

Objective: Hashimoto’s thyroiditis (HT) is the most common form of thyroiditis in childhood. In addition to thyroid ultrasonography, shear-wave elastography (SWE) can evaluate thyroid parenchyma tissue stiffness, and more detailed findings can be obtained with this method. We aimed to evaluate the relationship between SWE values and clinical, biochemical and hormonal parameters of patients with HT and in healthy individuals. Methods: We compared 46 newly diagnosed HT cases with 46 healthy controls. We examined the effect of all metabolic parameters and thyroid-related markers on SWE values. Results: The mean SWE values in those patients with euthyroid HT were 12.5±5.1 kilopascal (kPa), whereas it was 8.2±2.82 kPa in healthy controls (p<0.001). Although the clinical [age, gender and body mass index (BMI)] and laboratory parameters (such as thyroid function tests, homeostasis model assessment of insulin resistance, insulin-like growth factor-1 values, which we think may affect SWE scores) of those children with HT and the healthy controls were statistically similar (p>0.05), except for their thyroid autoantibodies and thyroglobulin, SWE values and thyroid volume were significantly higher in those individuals with HT (p<0.001). Multiple linear regression analysis was performed to evaluate the direction and degree of the effect of the variables on thyroid elasticity scores. It was observed that age (p=0.002), BMI standard deviation score (SDS) (p=0.04) and anti-thyroid peroxidase (p=0.008) levels were effective on the thyroid elasticity score in the regression model. We detected a SWE cut-off value of 9.68 kPa with 68% sensitivity and 72% specificity, a 70% positive predictive value, and a 69% negative predictive value in thyroid elastography when differentiating between cases with HT and healthy controls. Conclusion: Our results show that no metabolic factor other than BMI SDS has any effect on SWE scores, especially in healthy children. There was a positive correlation between BMI SDS and SWE in healthy children (r=0.353; p=0.02), but not in those patients with HT (r=0.196; p=0.19). Likewise, age is another factor affecting SWE only in healthy children. We do not recommend routine evaluation of any laboratory parameters other than thyroid functions before thyroid elastography.

show abstract

The Diagnostic Value of the American College of Radiology Thyroid Imaging Reporting and Data System Classification and Shear-Wave Elastography for the Differentiation of Thyroid Nodules

Cited by 11 publications

References 42 publications

Elastografie von Schilddrüsenknoten

Elastografie von Schilddrüsenknoten

Multimodal ultrasound imaging: A method to improve the accuracy of diagnosing thyroid TI‐RADS 4 nodules

Factors Affecting Thyroid Elastography in Healthy Children and Patients with Hashimoto’s Thyroiditis

Contact Info

Product

Resources

About