The diagnostic value of image guided percutaneous fine needle aspiration biopsy in equivocal mediastinal masses

Güllüoğlu, Mine; Kılıçaslan, Zeki; Toker, Alper; Kalayci, Goksel; Yılmazbayhan, Dilek

doi:10.1007/s00423-006-0029-5

Cited by 14 publications

(3 citation statements)

References 9 publications

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“…Similar was observed in the study by Dixit R. 4 The diagnostic accuracy was 100% and 63.63% by LBC and CC technique of the mediastinal masses. This was well related with the findings of studies by Shaheen et al and Güllüoglu et al 28,29 Thin prep smears were adequate for evaluation in 90.36% (75) cases. Conventional smears made from aspirates of only 53 patients (63.86%) were adequate to make a diagnosis.…”

Section: Discussionsupporting

confidence: 87%

Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses

et al. 2020

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Background: Fine Needle Aspiration Cytology (FNAC) has proven to be less costly and less invasive procedure than biopsy for diagnosing benign and malignant lesions. Of the two methods liquid based cytology (LBC) and conventional cytology (CC), LBC has been standardized as more efficacious in reporting in Gynaecological cases. But, this is still lacking in non-gynaecological cases and many studies are now focusing on studying LBC due to its proven advantages in Pap smear evaluation.Methods: An observational study of 72 patients with lung mass and 11 with mediastinal mass was done for a period of six months in a tertiary care hospital in Gurugram to compare the diagnostic efficacy of LBC and CC in fine needle aspirates from lung/mediastinal mass.Results: Of the 83 cases, reporting of LBC was adequate in 75 cases and CC in only 53 cases. LBC was better when differentiating malignant and benign lesions than CC. CC smears had better cellularity in comparison to LBC smears (36%), but rest cytological features of cytoplasmic detailing, cell architecture, less background debris and blood were all more appreciable in LBC smears than CC preparations.Conclusions: LBC is a better method than conventional smear for smear preparation and processing of aspirates obtained from lung and mediastinal mass.

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Section: Discussionsupporting

confidence: 87%

Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses

et al. 2020

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“…Our study had a diagnostic accuracy of 98% which is better than the diagnostic success rates of other studies [4]. Reported accuracy rates of CT guided percutaneous needle aspiration/biopsy ranges from 64%-97% with a small risk of complications, and these results were observed by B Morrissey et al [1], Westcott JL et al [3].…”

Section: Discussionsupporting

confidence: 54%

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Vasanthraj¹,

Dev²,

Santosham³

et al. 2018

Int J Surg Med

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Causes of mediastinal lymphadenopathy are many, ranging from reactive lymphadenopathy to malignancy. With the high incidence of tuberculosis in India, we aimed to determine the incidence of malignancy in mediastinal nodes with no primary lung lesion using computed tomography (CT)-guided biopsy as an evaluating tool and highlighting the superiority of this procedure over others described in the literature.

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“…[141516] The diagnostic accuracy of mediastinal lesions approached in the present study was 89.9% that is similar to the diagnostic yield in studies by Shaheen et al . [3] and Güllüoglu et al .,[17] superior compare to studies by Morrissey et al . [18] (77%), Assaad et al .…”

Section: Discussionmentioning

confidence: 88%

Diagnostic evaluation of mediastinal lesions: Analysis of 144 cases

et al. 2017

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Background:Mediastinum is a “Pandora's box” with many neoplastic and nonneoplastic lesions. The purpose of this study was to analyze our institutional experience of mediastinal lesions on fine-needle aspiration cytology (FNAC) and/or biopsy.Materials and Methods:This study was an analysis of 144 patients who had undergone ultrasound-guided FNAC and/or core biopsy for mediastinal lesions.Results:A total of 144 cases of suspected mediastinal masses were seen, and in 139 cases, tissue diagnosis was attempted. Out of 139 cases, 93 cases were neoplastic in nature (67%), 32 were nonneoplastic (23%), and 14 remained inconclusive (10%). Among neoplastic mediastinal lesions, metastatic carcinoma (37.4%) was the most common neoplastic lesion, followed by non-Hodgkin's lymphoma (12.2%), Hodgkin's lymphoma (7.1%), thymic lesions (3.5%), etc. Among nonneoplastic conditions, tuberculosis was the most common lesion (20.1%). An accurate tissue diagnosis was made in 89.9% cases by FNAC or core biopsy of mediastinal lesions in this study. Procedure-related mortality was nil. Complications were mostly minor and included chest pain in 24.5%, small pneumothorax in 13.6% requiring closed tube thoracostomy in 1.4%, and scanty hemoptysis in 9.3% cases.Conclusion:Neoplastic mediastinal lesions are more common than nonneoplastic lesions, with metastatic carcinoma being the most common cause followed by tuberculosis. A wide variety of lesions observed in this study stress on the importance of cytohistological diagnosis in all cases of mediastinal lesions for the final diagnosis and management planning. A guided FNAC or core biopsy is still accurate, well tolerated, and devoid of major complications.

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The diagnostic value of image guided percutaneous fine needle aspiration biopsy in equivocal mediastinal masses

Abstract: Image guided percutaneous FNA biopsy is a safe and highly accurate diagnostic method for equivocal mediastinal masses.

Cited by 14 publications

References 9 publications

Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses

Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Diagnostic evaluation of mediastinal lesions: Analysis of 144 cases

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