The diagnostic utility of lymph node cytology samples in dogs and cats

Amores-Fuster, I.; Cripps, Peter; Graham, Peter; Marrington, A. M.; Blackwood, Laura

doi:10.1111/jsap.12303

Cited by 32 publications

(61 citation statements)

References 10 publications

(9 reference statements)

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“…In feline samples, the association was not significant, although this may be due to a smaller sample size (Amores-Fuster et al 2015 ). Of the canine samples, 73% were diagnostic, and of the 199 feline lymph nodes aspirates evaluated, 86% were considered diagnostic.…”

Section: Abdominal Lymph Nodesmentioning

confidence: 86%

“…Of the canine samples, 73% were diagnostic, and of the 199 feline lymph nodes aspirates evaluated, 86% were considered diagnostic. The most common reasons for a non-diagnostic sample included the absence of nucleated cells, cell disruption and a low yield (Amores-Fuster et al 2015 ). It is important to note that the lymph node samples in this study were not specifically from the abdomen, and in our experience, obtaining samples from abdominal lymph nodes is more likely to be non-diagnostic compared with subcutaneous lymph nodes.…”

Section: Abdominal Lymph Nodesmentioning

confidence: 87%

“…In a study of 1274 canine lymph node aspirates from various locations, the median number of slides submitted per patient following lymph node aspiration was three, and in dogs, the number of slides was significantly associated with an increased probability of obtaining both a diagnostic specimen and a cytological diagnosis (Amores-Fuster et al 2015 ). In feline samples, the association was not significant, although this may be due to a smaller sample size (Amores-Fuster et al 2015 ).…”

Section: Abdominal Lymph Nodesmentioning

confidence: 99%

“…The most common diagnosis from canine lymph node FNAs is lymphoma (27·5%) (Sapierzyński & Micuń 2009, AmoresFuster et al 2015, whilst in cats, reactive hyperplasia is most commonly diagnosed (32%) (Amores-Fuster et al 2015 ).…”

Section: Abdominal Lymph Nodesmentioning

confidence: 99%

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Fine needle aspiration of abdominal organs: a review of current recommendations for achieving a diagnostic sample

Liffman

Courtman

2017

J of Small Animal Practice

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With the improved accessibility to ultrasound, fine needle aspiration of abdominal organs is now performed frequently in many veterinary practices. Despite this, there are many ‘unknowns’ as to the best method to produce a high‐quality sample. This report begins by highlighting recent literature on the risks and benefits of abdominal fine needle aspiration. It follows with recommendations about the equipment and method best suited to the procedure, including needle and syringe size and aspiration versus non‐aspiration techniques. Various smear preparations and laboratory submission requirements are also discussed. The final aspect of the review more specifically discusses fine needle aspiration of specific abdominal organs: the liver, kidney, spleen, pancreas, urinary bladder, prostate and abdominal lymph nodes.

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Section: Abdominal Lymph Nodesmentioning

confidence: 86%

Section: Abdominal Lymph Nodesmentioning

confidence: 87%

Section: Abdominal Lymph Nodesmentioning

confidence: 99%

Section: Abdominal Lymph Nodesmentioning

confidence: 99%

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Fine needle aspiration of abdominal organs: a review of current recommendations for achieving a diagnostic sample

Liffman

Courtman

2017

J of Small Animal Practice

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“…However, it has been suggested that in veterinary medicine excisional biopsy of the lymph node and histopathology should only be considered when cytological examination gives an inconclusive result (Messick 2008, Comazzi et al 2014. Cytology is a cheap, easy to perform, safe and reliable method of lymphoma diagnosis with high accuracy compared to histopathological examination (Amores-Fuster et al 2015). In human oncology, cytological examination allows non-Hodgkin lymphoma to be recognized in 80-95% of cases; additionally, subtyping is possible in 67-86% of lymphomas (Das 1999, Alam et al 2010.…”

Section: Application Of Cytology In Canine Lymphomasmentioning

confidence: 99%

Cytodiagnostics of canine lymphomas – possibilities and limitations

Sapierzyński¹,

Kliczkowska-Klarowicz²,

Jankowska³

et al. 2016

Polish Journal of Veterinary Sciences

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Malignant lymphomas are one of the most common malignant tumours occurring in dogs. The basic method of lymphoma diagnosis in human, as well as in canine oncology is histopathology supported by immunohistochemistry. It was suggested that in veterinary medicine excisional biopsy of lymph node and histopathology should be considered only where the cytologic diagnosis is equivocal or needs to be confirmed. There are at least three basic reasons for which cytological examination ought to be accepted as a sufficient and reliable diagnostic method for lymphoma in dogs. Firstly, most dog owners consider the fine-needle biopsy as an acceptable non-harmful method of sample collection. Secondly, an increasing number of studies recommend cytology as an accurate test for diagnosing and subtyping canine lymphoma. Finally, the vast majority of canine lymphoma subtypes belong to 4-5 categories characterized by a typical cytological picture. Immunocytochemical staining of cytological smears gives new diagnostic possibilities, such as detection of markers better characterizing given growth or a potential goal for target therapy in individual cases (for example inhibitors of platelet-derived growth factor).

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