The diagnostic utility of diffusion‐weighted magnetic resonance imaging and high‐resolution computed tomography for cholesteatoma: A meta‐analysis

Xun, Mengzhao; Liu, Xu; Sha, Yongfang; Zhang, Xin; Liu, Jianping

doi:10.1002/lio2.1032

Cited by 3 publications

(6 citation statements)

References 31 publications

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“…This percentage is considerably better than previous studies such as Nash et al [9], who reported a sensitivity of 63.6%. However, our reported sensitivity was lower than other studies [88%, 89.3%, and 100.0%] [10][11][12] . The studies by Xun et al [10] and Laske et al [11] included a large sample of patients, and the study by Osman et al [12] included only subjects with recurrent conditions.…”

Section: Discussioncontrasting

confidence: 95%

“…However, our reported sensitivity was lower than other studies [88%, 89.3%, and 100.0%] [10][11][12] . The studies by Xun et al [10] and Laske et al [11] included a large sample of patients, and the study by Osman et al [12] included only subjects with recurrent conditions. This could explain the heterogeneity of sensitivities.…”

Section: Discussioncontrasting

confidence: 95%

“…This could explain the heterogeneity of sensitivities. The specificity of DWI in detecting cholesteatoma was 100%, which is better than most studies [90% for Osman et al [12] and 93% for Xun et al [10] ].…”

Section: Discussionmentioning

confidence: 56%

“…It also had an accepted sensitivity and the smallest detectable size when compared to other studies, as described previously. In addition, the CT assessment had a sensitivity of 52%, which is better than Osman et al [12], who reported a value of 47.6%, and less than Xun et al [10] , who reported a value of 68%. The first author reported values for recurrent conditions, while the second author included a larger sample of subjects [80 patients].…”

Section: A B D C F Ementioning

confidence: 61%

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Optimizing Cholesteatoma Assessment: Utilizing of Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography Imaging for Diagnostic Precision and Surgical Excellence

Hamroush,

El-Deek,

Abdelazim

et al. 2024

International Journal of Medical Arts

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Section: Discussioncontrasting

confidence: 95%

Section: Discussioncontrasting

confidence: 95%

Section: Discussionmentioning

confidence: 56%

Section: A B D C F Ementioning

confidence: 61%

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Optimizing Cholesteatoma Assessment: Utilizing of Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography Imaging for Diagnostic Precision and Surgical Excellence

Hamroush,

El-Deek,

Abdelazim

et al. 2024

International Journal of Medical Arts

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“…While our study centered on HRCT, it's important to acknowledge the complementary role of MRI in cases where intricate soft tissue characterization is essential. Incorporating advanced imaging modalities like diffusion-weighted (DW) MRI, as recommended by recent studies [ 12 ], could further enhance our understanding of cholesteatoma and its differentiation from other middle ear pathologies. However, given the limitations of our study, exploring these innovative approaches would require separate investigations in the future.…”

Section: Discussionmentioning

confidence: 99%

High-Resolution Computed Tomography and Intraoperative Correlation in Cholesteatoma: Enhancing Preoperative Evaluation and Surgical Management

Kapoor,

Nimkar

et al. 2023

Cureus

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Introduction: Cholesteatoma, a hazardous non-neoplastic lesion of the temporal bone, is prevalent in socio-economically disadvantaged groups in developing nations like India. Timely detection and surgical intervention are essential for effective management. High-resolution computed tomography (HRCT) has revolutionized the assessment of temporal bone pathology, though its role in preoperative evaluation remains debated. This study aimed to validate HRCT's utility in diagnosing cholesteatoma, compare its findings with intraoperative observations, and assess sensitivity and specificity. Methods: This diagnostic accuracy study was conducted at a tertiary care center in Western India, from March 2021 to November 2022. HRCT findings of 54 cholesteatoma patients were evaluated and compared with intraoperative findings. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Cohen's kappa coefficient were calculated. Results: HRCT demonstrated a sensitivity exceeding 90% in identifying scutum erosion, mastoid sclerosis, and abnormalities in the tympanic membrane, along with a specificity surpassing 90% in detecting various conditions, including facial canal erosion, sinus plate erosion, lateral semicircular canal erosion, erosion of the posterior wall of the external auditory canal, and abnormalities in the tympanic membrane. Furthermore, HRCT exhibited an accuracy of over 90% in detecting most pathologies. There was a perfect or near-perfect agreement observed for abnormal tympanic membrane, sinus plate erosion, mastoid sclerosis, and erosion of the posterior wall of the external auditory canal (with kappa values > 0.8). Moderate to fair agreement was noted for other pathologies. Conclusion: HRCT offered precise detection of the majority of pathologies, thereby facilitating surgical planning. However, the presence of limitations in distinguishing specific abnormalities highlights the significance of utilizing HRCT in tandem with other diagnostic modalities to ensure meticulous diagnosis and effective treatment planning.

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Factors Influencing Treatment Success in Cholesteatoma Management: A Cross-Sectional Study

Alshehri,

Al Shalwan,

Oraydan

et al. 2024

JCM

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Background/Objectives: Cholesteatoma presents significant management challenges in otolaryngology. This study aimed to delineate the influence of demographic and clinical characteristics, preoperative imaging, and surgical approaches on treatment success in cholesteatoma management. Methods: A cross-sectional analytical study was conducted at the Otolaryngology Department of the University Hospital from January 2021 to December 2022. It included 68 patients diagnosed with cholesteatoma, focusing on three objectives: assessing the impact of demographic and clinical characteristics on treatment outcomes, evaluating the predictive value of preoperative imaging findings, and analyzing the influence of surgical factors. Results: The study population predominantly consisted of male (56%) and Saudi (81%) patients, with an average age of 45 years. Logistic regression revealed that older age (OR: 1.05), male gender (OR: 0.63), and non-Saudi Arab ethnicity (OR: 2.14) significantly impacted treatment outcomes. Clinical characteristics such as severe disease severity (OR: 3.00) and longer symptom duration (OR: 0.96) also influenced treatment success. In preoperative imaging, labyrinthine fistula (Regression Coefficient: 0.63) and epidural extension (Coefficient: 0.55) emerged as key predictors. The surgical factors that significantly affected the outcomes included the extent of surgery (Complete Removal OR: 3.32) and the use of endoscopic approaches (OR: 1.42). Conclusions: This study highlights that patient demographics, clinical profiles, specific preoperative imaging features, and surgical strategies multifactorially determine cholesteatoma treatment success. These findings suggest the necessity for a tailored approach in cholesteatoma management, reinforcing the importance of individualized treatment plans based on comprehensive preoperative assessments.

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The diagnostic utility of diffusion‐weighted magnetic resonance imaging and high‐resolution computed tomography for cholesteatoma: A meta‐analysis

Abstract: Objective: The purpose of this meta-analysis was to compare the efficiency of highresolution computed tomography (HRCT) and diffusion-weighted magnetic resonance imaging (DWI) in guiding the diagnosis of middle ear cholesteatoma in clinical practice.

Cited by 3 publications

References 31 publications

Optimizing Cholesteatoma Assessment: Utilizing of Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography Imaging for Diagnostic Precision and Surgical Excellence

Optimizing Cholesteatoma Assessment: Utilizing of Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography Imaging for Diagnostic Precision and Surgical Excellence

High-Resolution Computed Tomography and Intraoperative Correlation in Cholesteatoma: Enhancing Preoperative Evaluation and Surgical Management

Factors Influencing Treatment Success in Cholesteatoma Management: A Cross-Sectional Study

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