The diagnostic efficacy of FDG-PET in the local recurrence of hilar bile duct cancer

Abstract

When used in combination with other modalities, FDG-PET offered useful information for the diagnosis of a local recurrence of HBC. This highly sensitive imaging approach also appeared to be useful for follow-up examination after irradiation therapy.

Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009

“…PET has been shown to be useful in monitoring tumor response to treatment. In a small series by Chikamoto et al [154] , PET had a sensitivity of 80% for detecting local recurrence after resection in patients with HCC. One of the limitations of PET is that patients with biliary inflammatory conditions such as PSC or cholangitis may have false positive results [152,155] while patients with mucinous CC may have falsely negative scans due to poor uptake of FDG [155] .…”

Clinical impact of whole body FDG-PET for recurrent biliary cancer: a multicenter study

“…Four groups have investigated the usefulness of FDG-PET or PET/CT for postoperative surveillance of patients with biliary cancer and reported a sensitivity of 89-100% and specificity of 93-100% [9][10][11][12]. Two authors demonstrated that PET or PET/CT showed better diagnostic accuracy for recurrence than CT [11,12].…”

“…Several studies describing the usefulness of FDG-PET for the differential diagnosis and initial diagnosis of biliary cancer have been published [5][6][7][8][9][10]. However, few studies have described the usefulness of FDG-PET for post-treatment evaluation [9][10][11][12].…”

PET/CT in Hepatobiliary-Pancreatic Tumors

“…Additionally, 18 F-FDG-PET/CT appears to be an encouraging method in postoperative monitoring of CCA recurrence. A small series by Chikamoto et al [20] found that PET/CT had a sensitivity of 80%; in these cases, conventional imaging is limited because of difficulties in differentiating tumor tissue and postoperative changes [21][22][23].…”