The developmental trajectory of1H-MRS brain metabolites from childhood to adulthood
Alice R. Thomson,
Hannah Hwa,
Duanghathai Pasanta
et al.
Abstract:Human brain development is ongoing throughout childhood, with for example myelination of nerve fibres and refinement of synaptic connections continuing until early adulthood.1H-Magnetic Resonance Spectroscopy (1H-MRS)can be used to quantify the concentrations of endogenous metabolites (e.g., glutamate and γ-aminobutyric acid (GABA)) in the human brain in vivo and so can provide valuable, tractable insight into the biochemical processes that support postnatal neurodevelopment. This can feasibly provide new insi… Show more
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