“…Regarding reverse transcriptase inhibitors, recent reports have linked tenofovir to the occurrence of osteomalacia and the Fanconi syndrome [12]. Other factors can also contribute to accelerate bone loss, such as nutritional deficiency, low serum calcium levels, immobilization, hypogonadism, hyperthyroidism, hyperparathyroidism, renal failure, use of opioids or heroin, use of corticosteroids, postmenopausal period, and alcohol intake higher than 16 g/ day [1,8].…”