The development of a quality assurance programme for HPV testing within the UK NHS cervical screening LBC/HPV studies

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer

“…Inter-laboratory or proficiency testing to ensure quality results across laboratories should be established. 50 While well validated in the research setting, additional studies of inter-laboratory comparability of HPV testing in the clinical laboratory setting would be helpful.…”

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer

“…Interlaboratory or proficiency testing to ensure quality results across laboratories should be established. 50 While well validated in the research setting, additional studies of interlaboratory comparability of HPV testing in the clinical laboratory setting would be helpful.…”

External quality assessment for molecular detection of human papillomaviruses

“…20,23,24 The current study, however, demonstrates good inter-laboratory reproducibility between over forty laboratories in different countries using a combination of at least eight different assays.…”

“…19 External quality assessment (EQA) of the cytological diagnosis of cervical cancer is well established in the UK. The introduction of direct HR HPV testing, into national screening programmes 20 with a primary objective of including the EQA for HPV within United Kingdom National External Quality Assessment Service (UK NEQAS) for Microbiology provision. The suitability of specimens for this UK NEQAS scheme was determined by distributing three 'Molecular detection of HPV' pilot distributions and assessing the methods used to analyse the data and participants' performance.…”