The determination of a new inhalational anaesthetic, sevoflurane, using an internal standard, xenon, by gas chromatography/mass spectrometry/selected ion monitoring

Abstract

A novel determination method for a new inhalation anaesthetic, sevoflurane, in a closed circuit in the presence of carbon dioxide absorbents is investigated using gas chromatography/selected ion monitoring with xenon as an internal standard. The decrease rate of sevoflurane with soda lime was 0.22% +/- 0.158/h (mean +/- SD), while that with baralyme was 0.57% +/- 0.115/h (mean +/- SD).

Cyclic voltammetry study of the electrocatalytic reduction of sevoflurane by a cobalt(III) Schiff base complex in the presence of oxygen

“…In addition, the concentration of these agents in a patient's blood must be monitored to ensure the patient's safety. The monitoring has been undertaken by measuring the concentration of these agents by different methods in the last two decades [6][7][8][9][10][11][12][13][14][15][16][17]. However, these methods require complicated and expensive instrumentation, professional operators, a time-consuming detection process, and complex pre-treatment steps.…”

Einfluss des Oxygenatormembrantyps auf die Plasmakonzentration des volatilen Anästhetikums Sevofluran und den Narkoseverlauf während Operationen mit extrakorporaler Zirkulation

“…In der Regel dient zur Verbindung zwischen dieser Apparatur und dem Oxygenatorgasauslass ein Gasprobenschlauch (Hickey et al 1996) (Domange 1956) rasch eine weite Verbreitung. Seither wurden gaschromatographische Untersuchungen von volatilen Anästhetika mehrfach beschrieben (Uyanik 1997, Miyano et. al 1993, Flynn et.…”