The determinants of vaccine hesitancy in China: A cross-sectional study following the Changchun Changsheng vaccine incident

Du, Fanxing; Chantler, Tracey; Francis, Mark R.; Sun, Fiona Yueqian; Zhang, Xuan; Han, Kaiyi; Rodewald, Lance; Yu, Hongjie; Tu, Shiliang; Larson, Heidi; Hou, Zhiyuan

doi:10.1016/j.vaccine.2020.09.075

Cited by 67 publications

(65 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, there has been very limited data on COVID-19 vaccination perception among employees of public health. According to our results, they showed the highest proportion of confidence regardless of demographic characteristics, no matter in vaccine, professional institute or the government, which is probably due to the public health attribute of vaccines [ 25 , 26 , 27 ], and a reflection of the nature that vaccines are more of public health issues in terms of disease prevention. On the contrary, nurses were found to report the lowest confidence.…”

Section: Discussionmentioning

confidence: 78%

Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Wang

Han

et al. 2021

Vaccines

View full text Add to dashboard Cite

Background: The SARS-CoV-2 vaccine has been widely rolled out globally in the general populations. However, specific data on vaccination confidence, willingness or coverage among health care workers (HCWs) has been less reported. Methods: A cross-sectional online survey was conducted to specify the basic data and patterns of vaccination confidence, willingness and coverage among HCWs nationwide. Results: In total, 2386 out of 2583 (92.4%) participants were enrolled for analysis, and the rates of confidence in vaccine, professional institutes and government were 75.1%, 85.2% and 85.4%, respectively. The overall vaccination coverage rate was 63.6% which was adjusted as 82.8% for participants under current medical conditions or having contraindications. Confidence in vaccine safety was shown to be the most related factor to willingness among doctors, nurses, medical technicians and hospital administrators, while confidence in vaccine effectiveness as well as trust in government played the key role in formulating public health employees’ willingness. 130 (7.1% of 1833) participants reporting willingness still not been vaccinated regardless of contraindications. Multivariate analysis among willingness participants showed that males, aged over 30 years, public health employees and higher vaccination confidence had significantly higher vaccination rates with ORs (95% confidence intervals) as 1.64 (1.08–2.49), 3.14 (2.14–4.62), 2.43 (1.46–4.04) or 2.31 (1.24–4.33). Conclusions: HCWs’ confidence, willingness and coverage rates to the vaccine were generally at high levels. Heterogeneity among HCWs should be considered for future vaccination promotion strategies. The population’s confidence in vaccination is not only the determinant to their willingness, but also guarantees their actual vaccine uptake.

show abstract

Section: Discussionmentioning

confidence: 78%

Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Wang

Han

et al. 2021

Vaccines

View full text Add to dashboard Cite

show abstract

“…Caregivers of all children visiting the sampled vaccination clinics on a given day during the survey period and from a class in the sampled kindergartens were invited to participate in our survey. Additional details on the sampling and recruitment methodology is reported elsewhere [31,32]. Caregivers were invited to complete questionnaires-by themselves, on their mobile phones, or in writing on the spot with assistance after informed consent was obtained.…”

Section: Data Collectionmentioning

confidence: 99%

Access to Vaccination Information and Confidence/Hesitancy towards Childhood Vaccination: A Cross-Sectional Survey in China

Chantler

Francis

et al. 2021

Vaccines

Self Cite

View full text Add to dashboard Cite

Access to vaccination information could influence public attitudes towards vaccination. This study investigated the number and types of vaccination-related information sources, and estimated their associations with vaccine confidence and hesitancy in China. In January 2019, we conducted a cross-sectional survey in China, and 2122 caregivers with children <6 years completed self-administered questionnaires. Logistic regressions were used to assess associations between caregivers’ primary information sources and vaccine confidence/hesitancy. A majority (72%) of caregivers had multiple sources of vaccination-related information. The proportions of caregivers reporting professional sources, media, and peers as primary information sources were 81%, 63%, and 26%. Internal migrants were less likely to get information from professional sources; more educated and wealthier caregivers reported more information sources and were more likely to get information from media and peers. Caregivers who reported professional information sources had significantly higher odds of being confident about the safety of vaccines and lower odds of being hesitant toward vaccination than those who did not. Caregivers who reported the media as a primary information source had significantly higher odds of being hesitant toward vaccination than those who did not. To address vaccine hesitancy, it is essential to promote universal access to professional vaccination-related information sources, and to use the media to disseminate evidence-based information and clarify misinformation. Health communication should target internal migrants, and more educated and wealthier caregivers.

show abstract

“…Besides, numerous problems and adverse reactions have continuously been exposed in the process of vaccine development in different countries [13][14][15]. Since people were found to be more hesitant about vaccination following negative vaccine incidents [16][17][18][19], it is unclear how the public's acceptance of the COVID-19 vaccine will be further affected in the current circumstance.…”

Section: Introductionmentioning

confidence: 99%

“…Vaccine hesitancy is not driven by a simple set of individual factors. The Confidence, Convenience, and Complacency (3Cs) model was used for grasping factors of vaccine hesitancy by the researchers [16,23,24]. Confidence is defined as the trust in the safeness and effectiveness of vaccines; the system that delivers them, including the health services and health professionals; and the policymakers.…”

Section: Introductionmentioning

confidence: 99%

Acceptance of a COVID-19 Vaccine Before it is Available in China During the Pandemic

Xu¹,

Liu²

2021

Int J Public Health

View full text Add to dashboard Cite

Objectives: China was believed to be the country with the world’s highest acceptance rate of the COVID-19 vaccine following several investigations. This study aims to explore the Chinese acceptance of a COVID-19 vaccine before it is made available, including its determinants.Methods: A cross-national online survey was conducted covering all 31 provinces of mainland China. The survey consists of the demographic variables, acceptance of a self-paid COVID-19 vaccine as the dependent variable, and the 3Cs factors (i.e., confidence, convenience, and complacency) as the independent variables.Results: Among the 1,532 participants, 57.9% accepted to get a self-paid COVID-19 vaccine. COVID-19 vaccine acceptors were more likely to be concerned about the effectiveness of the vaccines, believe that they were at risk of COVID-19 infection, have a high perceived susceptibility of COVID-19, and trust in the health care system.Conclusion: Findings indicate that the critical task in the early stage of the COVID-19 vaccine development in China is to increase the tolerance to some intuitive concerns about the vaccines, put more emphasis on the communication of the saliency of the disease threats, and effectively translate people’s trust in the government into vaccine acceptance.

show abstract

The determinants of vaccine hesitancy in China: A cross-sectional study following the Changchun Changsheng vaccine incident

Cited by 67 publications

References 28 publications

Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Willingness and SARS-CoV-2 Vaccination Coverage among Healthcare Workers in China: A Nationwide Study

Access to Vaccination Information and Confidence/Hesitancy towards Childhood Vaccination: A Cross-Sectional Survey in China

Acceptance of a COVID-19 Vaccine Before it is Available in China During the Pandemic

Contact Info

Product

Resources

About