Enterprise and entrepreneurship are well-known phenomena that have their history development of over 300 years. However, in relation to the family business they are still not well explored in the literature of management. Based on the overview of management literature, this article is an attempt to construct a theoretical framework for the purpose of comparative analysis of family business and entrepreneurship issues in Poland and in Vietnam. As a result, their similarities and differences are revealed in order to propose adequate solutions and recommendations for business and authority to support and promote this specific business activity towards their prosperity and high performance.