The detection of venous thrombosis of the legs using 125I-labelled fibrinogen

Flanc, C; Kakkar, Vijay V.; Clarke, Maxine

doi:10.1002/bjs.1800551007

Cited by 435 publications

(137 citation statements)

References 5 publications

Supporting

Mentioning

130

Contrasting

Unclassified

Order By: Relevance

“…The previously reported insensitivity of this technique fo r detection of deep venous thrombosis of the thigh (Flanc et at., 1968) was not apparent in this study. Half of the positive leg scans recorded in this study indicated DVT in the thigh.…”

Section: Discussionmentioning

confidence: 94%

Deep venous thrombosis in acute spinal cord injury: a comparison of 125I fibrinogen leg scanning, impedance plethysmography and venography

et al. 1976

View full text Add to dashboard Cite

Abstract. Twenty acute spinal cord injury patients were surveyed for deep venous thrombosis (DVT) by 1251 fibrinogen leg scanning, impedance plethysmography (IPG), and venography. Leg scanning was a more sensitive indicator of thrombotic events than IPG or venography. IPG was a reliable indicator of accumulated thrombosis. The incidence of DVT assessed by leg scanning alone was 100 per cent. Its occurrence as determined by either of the screening techniques was found to be considerably greater than those of previous reports.

show abstract

Section: Discussionmentioning

confidence: 94%

Deep venous thrombosis in acute spinal cord injury: a comparison of 125I fibrinogen leg scanning, impedance plethysmography and venography

et al. 1976

View full text Add to dashboard Cite

show abstract

“…From several scintigraphic methods developed to detect DVT only IFS has been thoroughly evaluated and introduced in clinical practice [72,[100][101][102][103]. The diagnosis of venous thrombosis by IFS is based on incorporation of circulating labelled fibrinogen into the thrombus, which is then detected by measuring increase of overlying surface radioactivity with an isotope detector.…”

Section: I-fibrinogen Scanning (1fs)mentioning

confidence: 99%

Diagnosis of deep vein thrombosis, an overview

Janssen

Wollersheim

Nováková

et al. 1996

The Netherlands Journal of Medicine

View full text Add to dashboard Cite

A bstractBecause clinical signs and symptoms are unreliable the diagnosis of deep vein thrombosis (DVT) should be objectified. Advantages and disadvantages of contrast venography, plethysmography, ultrasound techniques, fibrino gen leg scanning, computer-assisted tomography, magnetic resonance imaging and blood tests are discussed. In patients with a first event of suspected DVT non-invasive methods like serial plethysmography or ultrasound testing are sensitive and specific enough to make a treatment decision. It is safe to withhold anticoagulants if the test remains normal within 1 week. In patients with suspected recurrent DVT new non-invasive techniques are being tested, but up to now the definitive objective diagnostic test continues to be contrast venography. In first period as well as in recurrent DVT D-Dimer testing could be an additional test to exclude active thromboembolism.

show abstract

“…However, other authors have reported, in phlebographic studies, that the incidence of venous thrombosis after pneumatic tourniquet varies from 10 to 60 per cent (Cohen et al 1973, Kroese & Stiris 1976. Evidence has been presented that the thrombosis appears already during the first postoperative hour (Flanc et al 1968, Negus et al 1968.…”

mentioning

confidence: 98%