The detection of the human papilloma virus during hyperplastic processes in the nose, ears and throat

Бойко, Н. В.; Panchenko, S N

doi:10.17116/otorino201782251-54

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…Хроническое вялотекущее воспаление, вызываемое персистенцией вирусных и бактериальных возбудителей, нередко приводит к стимуляции ангиогенеза в слизистой оболочке полости носа [10]. Вновь образованные сосуды, как правило, характеризуются неравномерностью диаметра, извитым ходом и наличием дистрофических изменений в эндотелии, что вызывает реологические нарушения, приводящие к их тромбозу с последующим формированием эрозий и участков некроза слизистой оболочки, которые становятся источниками кровотечения [21].…”

Section: таблица 1 соотношение патологических изменений полости носа ...unclassified

Incidence of Nasal Bacterial Colonization in Children with Recurrent Epistaxis

Бойко¹,

Летифов²,

Kurbatova³

2023

Педиатрия. Восточная Европа

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Цель. Изучение частоты колонизации полости носа Staphylococcus aureus у детей с рецидивирующими носовыми кровотечениями неясной этиологии. Материалы и методы. Исследованы 28 детей в возрасте от 4 до 12 лет, страдающих рецидивирующими носовыми кровотечениями (НК) неясной этиологии. Помимо общеклинического исследования, позволившего исключить наличие нарушений гемостаза и патологии сосудистой стенки, произведено бактериологическое исследование передних отделов полости носа. Контрольную группу составили 28 детей, поступивших на плановое хирургическое лечение в лор-отделение, не страдающих носовыми кровотечениями. Результаты. При осмотре полости носа у детей с рецидивирующими НК отмечено более частое присутствие корок и видимой сети сосудов в передних отделах перегородки носа, чем в контрольной группе. При бактериологическом исследовании у детей с рецидивирующими НК у 64,28% обнаружен S. aureus, в то время как в контрольной группе он присутствовал у 17,85% детей. Заключение. Колонизация полости носа S. aureus вызывает вялотекущее воспаление, стимулирующее новообразование патологических сосудов в СОН, что приводит к возникновению НК. Purpose. To study the incidence of nasal colonization by Staphylococcus aureus in children with recurrent epistaxis of unclear etiology. Materials and methods. The study involved 28 children aged 4 to 12 years suffering from idiopathic recurrent epistaxis. Along with common clinical examination allowing excluding hemostasis disorders and vascular wall pathology, bacteriological examinations of the nasal cavity were performed. The control group consisted of 28 children admitted for surgical treatment in the ENT department, who did not suffer from epistaxis. Results. When examining the nasal cavity in children with recurrent epistaxis, a more frequent presence of crusts and a visible network of vessels in the anterior region of the nasal septum were noted than in the control group. Bacteriological examination of children with recurrent epistaxis revealed S. aureus in 64.28%, while in the control group it was present in 17.85% of children. Conclusion. Colonization of the nasal cavity with S. aureus causes low-grade inflammation stimulating the angiogenesis of pathological vessels in the nasal mucosa, which leads to the development of epistaxis.

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Section: таблица 1 соотношение патологических изменений полости носа ...unclassified

Incidence of Nasal Bacterial Colonization in Children with Recurrent Epistaxis

Бойко¹,

Летифов²,

Kurbatova³

2023

Педиатрия. Восточная Европа

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Epistaxis and arterial hypertension: a pathogenic link

Бойко¹

2021

Vestn. otorinolaringol.

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Inverted Papilloma against a Background of Bilateral Rhinosinusitis Polyposa with Viscous Mucin (Clinical Case)

Pestova

Савельева

Азнабаева

et al. 2018

Kreativnaâ hirurgiâ i onkologiâ

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Introduction. Rhinosinusitis polyposa consists in a chronic inflammation of the mucous membrane of the nose and paranasal sinuses, followed by recurrent growth of polyps and characterised by a high prevalence. Nasal polyps may be associated with the presence of viscous mucin; their characteristic CT signs are hyperostosis of the walls of the affected sinuses and thinning cavity walls until the bone is destroyed, this being a sign of aseptic osteomyelitis. The same sign is typical for inverted papilloma, the most common benign tumour of the nose and sinuses.Materials and methods. The present article presents a clinical observation. What makes it interesting is that a benign tumour was diagnosed against the background of bilateral rhinosinusitis polyposa. The clinical picture did not have nasal bleeding, which is typical for inverted papilloma; this was most likely due to the initial growth of the tumour. Thickening bone structures (hyperostosis) was balanced due to the pathogenetic peculiarities of the rhinosinusitis polyposa development with viscous mucin. Inverted papilloma was suspected during rhinoscopy, which revealed asymmetric growth of polyps. Final verification of the clinical diagnosis was carried out following computerised tomography of the nose and paranasal sinuses and histological examination of biopsy material.Results and discussion. This clinical case is of interest due to rhinocytogram data suggesting a viral and inflammatory etiology of the development of inverted papilloma. Therefore, the observed nucleoli of the nuclei of the columnar epithelium are characteristic of intracellular infection — in particular, viral. Remodelling of cells of the cylindrical epithelium is a sign of chronic inflammatory process.Conclusion. Thus, accurate performance of the diagnostic algorithm with histological verification of all removed material allows the identification of a neoplasm of the nasal cavity even in difficult cases, along with other diseases of the nasal cavity. Rhinocytogram data can help suggest the etiology of the intracellular type of infection in the epithelial cell and pathogenesis of inverted papilloma in a particular case.

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The detection of the human papilloma virus during hyperplastic processes in the nose, ears and throat

Cited by 3 publications

References 21 publications

Incidence of Nasal Bacterial Colonization in Children with Recurrent Epistaxis

Incidence of Nasal Bacterial Colonization in Children with Recurrent Epistaxis

Epistaxis and arterial hypertension: a pathogenic link

Inverted Papilloma against a Background of Bilateral Rhinosinusitis Polyposa with Viscous Mucin (Clinical Case)

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