The detection of human papillomavirus–16 in squamous cell carcinoma of the nail unit: A case series

Dika, Emi; Venturoli, Simona; Patrizi, Annalisa; Piraccini, Bianca Maria; Fanti, Pier ­Alessandro; Barbieri, Daniela; Nocera, Martina; Chessa, Marco Adriano; Landini, Maria Paola; Plaça, M. La

doi:10.1016/j.jaad.2016.08.063

Cited by 13 publications

(12 citation statements)

References 6 publications

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“…We speculate that more frequent exposure of the hands to trauma, oncogenic agents, and pathogens may have contributed to such results. Especially, human papillomavirus (HPV), which can be transmitted via direct contact, was frequently detected in Bowen's Disease and squamous cell carcinoma of the nail unit . Further exploration of this potential association is needed.…”

Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma of the nail unit: a retrospective review of 19 cases in Asia and comparative review of Western literature

Lee

Kim

et al. 2018

Int J Dermatology

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Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma of the nail unit: a retrospective review of 19 cases in Asia and comparative review of Western literature

Lee

Kim

et al. 2018

Int J Dermatology

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“…Bowen's disease consists of an intraepithelial dysplasia which may appear anywhere in the skin and that has been linked to HPV as well, e.g., to HPV56 [50] and HPV58 [51]. Those cases found in the skin of the genital area and around the nails are more likely to be associated with HPV [52][53][54][55].…”

Section: Penile and Vulvar Carcinomamentioning

confidence: 99%

Viruses and Skin Cancer

Becerril

Corchado-Cobos

García-Sancha

et al. 2021

IJMS

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Advances in virology and skin cancer over recent decades have produced achievements that have been recognized not only in the field of dermatology, but also in other areas of medicine. They have modified the therapeutic and preventive solutions that can be offered to some patients and represent a significant step forward in our knowledge of the biology of skin cancer. In this paper, we review the viral agents responsible for different types of skin cancer, especially for solid skin tumors. We focus on human papillomavirus and squamous cell cancers, Merkel cell polyomavirus and Merkel cell carcinoma, and human herpesvirus 8 and Kaposi’s sarcoma.

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“…). The pathogenesis is not fully known but possible causes include chronic radiodermatitis, tobacco use, traumas and HPV infections . The causative role of HPV has been correlated with recurrences after surgical excision .…”

Section: Sccmentioning

confidence: 99%

“…The pathogenesis is not fully known but possible causes include chronic radiodermatitis, tobacco use, traumas and HPV infections. 1,6,7,9,10 The causative role of HPV has been correlated with recurrences after surgical excision. 1 Photodynamic therapy with methyl aminolevulinate, CO 2 laser, 5-fluorouracil with or without prior curettage, imiquimod 5% cream, electrochemotherapy with bleomycin and bleopuncture with imiquimod cream have been reported as effective treatments, although surgery is the most appropriate treatment, considering the possibility of local invasion and bone involvement.…”

Section: Sccmentioning

confidence: 99%

Mohs micrographic surgery for nail unit tumours: an update and a critical review of the literature

Lambertini

Piraccini

Fanti

et al. 2018

Acad Dermatol Venereol

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Mohs micrographic surgery (MMS) is a good treatment option for epithelial neoplasms, especially when localized in areas where tissue conservation is crucial, such as the nail unit (NU). MMS is a method of radical excision offering high cure rates due to the margin control and functional preservation. Our aim is to provide a review on the use of MMS for the treatment of the most common nail tumours. We revised the current literature on the use of MMS to treat malignant neoplasms (Bowen's disease, squamous cell carcinoma, melanoma, basal cell carcinoma, keratoacanthoma, carcinoma cuniculatum) and benign neoplasms (onychomatricoma and glomus tumour). MMS represents a successful surgical option for nail tumours, firstly in terms of tissue conservation: the NU anatomy is complex and the preservation of the component structures is imperative for its functionality. Secondly, due to the surgical radicality, which is essential not only for the clearing of malignant tumours, but also for benign cases, in order to reduce recurrences. Although a conservative treatment of NU melanoma with MMS has been proposed, in our experience, the conservative approach with functional surgery is a good option for the treatment of non-invasive melanoma (in situ and Ia).

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The detection of human papillomavirus–16 in squamous cell carcinoma of the nail unit: A case series

Cited by 13 publications

References 6 publications

Squamous cell carcinoma of the nail unit: a retrospective review of 19 cases in Asia and comparative review of Western literature

Squamous cell carcinoma of the nail unit: a retrospective review of 19 cases in Asia and comparative review of Western literature

Viruses and Skin Cancer

Mohs micrographic surgery for nail unit tumours: an update and a critical review of the literature

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