The design of postemergence phenylurea herbicides using physiochemical parameters and structure-activity analyses

Cross, B.P.; Hoffman, Peggy P.; Santora, George T.; Spatz, David M.; Templeton, Andrew R.

doi:10.1021/jf00116a018

J. Agric. Food Chem.

1983

DOI: 10.1021/jf00116a018

|View full text |Cite

The design of postemergence phenylurea herbicides using physiochemical parameters and structure-activity analyses

B.P. Cross¹,

Peggy P. Hoffman²,

George T. Santora³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1985

1995

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 7 publications

References 2 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Structure‐activity relationships among the imidazolinone herbicides

Ladner¹

1990

Pestic. Sci.

View full text Add to dashboard Cite

The structure of the imidazolinone herbicides consists of three distinct moieties: the imidazolinone ring, the carboxylic acid and the backbone. The effect of changes in each of these on herbicidal activity, crop selectivity and AHAS enzyme inhibition has been studied. Though both whole-plant and enzyme activity were drastically affected by changes in the carboxylic acid or imidazolinone ring portions of the molecule, a variety of backbones and of substituents on the backbones afforded good activity. Methyl-isopropyl was found to be the best combination of substituents on the imidazolinone ring. While pyridine backbones generally gave the most active herbicides, benzene backbones led to the strongest enzyme inhibition. A QSAR study in the pyridine series generated two equations which proved usefirl for guiding the analog program toward the synthesis of potent heteropyridyl compounds. Selectivity in wheat is dependent upon di,fferences in the rate of metabolism of key groups. Rapid metabolism of either the imidazolinone ring or backbone alkyl groups occurs rapidly in soybeans compared with susceptible weeds.

show abstract

Structure‐activity relationships among the imidazolinone herbicides

Ladner¹

1990

Pestic. Sci.

View full text Add to dashboard Cite

show abstract

Characterization of new photosynthesis‐inhibiting imidazolidine derivatives. 1. Interpretation of post‐emergence herbicidal performance from photosynthesis‐inhibiting activity and systemicity

et al. 1995

View full text Add to dashboard Cite

An attempt was made to account for quantitatively measured herbicidal performance of foliage-applied 5-hydroxy-3-methyl-2-0x0-imidazolidine-1carboxamide derivatives by their photosynthesis-inhibiting activity and systemicity. Photosynthesis-inhibiting activity was estimated from the increase of chlorophyll fluorescence intensity in Chlorella vulgaris Beijer cells measured by a microplate scanner, and systemicity was also evaluated by computer-aided chlorophyll fluorescence imaging. The highest herbicidal performance was recorded for N-cyclohexyl-5-hydroxy-3-methyl-2-oxo-imidazo~idine-l-carboxamide, a compound with the second strongest photosynthesis-inhibiting activity and intermediate systemicity. Though neither photosynthesis-inhibiting activity nor systemicity showed significant correlation with the actual herbicidal performance in simple regression analyses, a high predictability was found for a multiple regression on both parameters as two independent variables, suggesting that these two factors work cooperatively in the field performance.

show abstract

Quantitative structure-activity relationships of herbicidal N′-substituted phenyl-N-methoxy-N-methylureas

Takemoto

Yoshida

Sumida

et al. 1985

Pesticide Biochemistry and Physiology

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The design of postemergence phenylurea herbicides using physiochemical parameters and structure-activity analyses

Cited by 7 publications

References 2 publications

Structure‐activity relationships among the imidazolinone herbicides

Structure‐activity relationships among the imidazolinone herbicides

Characterization of new photosynthesis‐inhibiting imidazolidine derivatives. 1. Interpretation of post‐emergence herbicidal performance from photosynthesis‐inhibiting activity and systemicity

Quantitative structure-activity relationships of herbicidal N′-substituted phenyl-N-methoxy-N-methylureas

Contact Info

Product

Resources

About