The design, development and application of electrochemical glutamate biosensors

Hughes, Gareth; Pemberton, R. M.; Fielden, Peter R.; Hart, John P.

doi:10.1016/j.trac.2015.10.020

Cited by 47 publications

(19 citation statements)

References 25 publications

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“…Multiple biosensors have been developed to measure glutamate levels in foods. Glutamate is a popular food additive in the form of monosodium glutamate to enhance umami flavor, and reduce salt intake [ 56 ]. However, it has been found to be harmful to human bodies and agricultural products.…”

Section: Biosensing In Food Safety and Securitymentioning

confidence: 99%

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

et al. 2018

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Current food production faces tremendous challenges from growing human population, maintaining clean resources and food qualities, and protecting climate and environment. Food sustainability is mostly a cooperative effort resulting in technology development supported by both governments and enterprises. Multiple attempts have been promoted in tackling challenges and enhancing drivers in food production. Biosensors and biosensing technologies with their applications, are being widely applied to tackling top challenges in food production and its sustainability. Consequently, a growing demand in biosensing technologies exists in food sustainability. Microfluidics represents a technological system integrating multiple technologies. Nanomaterials, with its technology in biosensing, is thought to be the most promising tool in dealing with health, energy, and environmental issues closely related to world populations. The demand of point of care (POC) technologies in this area focus on rapid, simple, accurate, portable, and low-cost analytical instruments. This review provides current viewpoints from the literature on biosensing in food production, food processing, safety and security, food packaging and supply chain, food waste processing, food quality assurance, and food engineering. The current understanding of progress, solution, and future challenges, as well as the commercialization of biosensors are summarized.

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Section: Biosensing In Food Safety and Securitymentioning

confidence: 99%

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

et al. 2018

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“…Therefore, optical and electrochemical sensing have emerged as an alternative. But, even though a great number of biosensors have been developed for neurotransmitter detection, they have not only been applied to AD, being mainly focused on water and food safety purposes [ 160 , 161 ].…”

Section: Electrochemical Biosensors For Alzheimer’s Disease Diagnomentioning

confidence: 99%

Electrochemical Biosensors Based on Nanomaterials for Early Detection of Alzheimer’s Disease

Toyos-Rodríguez

Alonso

Escosura‐Muñiz

2020

Sensors

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Alzheimer’s disease (AD) is an untreatable neurodegenerative disease that initially manifests as difficulty to remember recent events and gradually progresses to cognitive impairment. The incidence of AD is growing yearly as life expectancy increases, thus early detection is essential to ensure a better quality of life for diagnosed patients. To reach that purpose, electrochemical biosensing has emerged as a cost-effective alternative to traditional diagnostic techniques, due to its high sensitivity and selectivity. Of special relevance is the incorporation of nanomaterials in biosensors, as they contribute to enhance electron transfer while promoting the immobilization of biological recognition elements. Moreover, nanomaterials have also been employed as labels, due to their unique electroactive and electrocatalytic properties. The aim of this review is to add value in the advances achieved in the detection of AD biomarkers, the strategies followed for the incorporation of nanomaterials and its effect in biosensors performance.

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“…15 Substrate materials for creating sensing platforms, including arrays, are primarily silicon or ceramic. 16 Strategies for immobilizing the enzyme onto the electrode surface include direct adsorption, covalent binding, cross-linking, 17 and entrapment in polymers (reviewed in Scouten et al, 18 Freire et al, 19 Putzbach et al 20 and Hughes et al 21 ). Immobilization of enzymes in polymeric membranes, especially electrochemically deposited polymers, [22][23][24][25][26][27][28][29][30][31][32][33][34] gained increasing attention due to a variety of factors, 23 particularly the ability to prevent interfering molecules from reaching the electrode.…”

Section: Introductionmentioning

confidence: 99%