The dependency on scale of power numbers of Rushton disc turbines

Bujalski, W.; Nienow, Alvin W.; Chatwin, S.; Cooke, Mike

doi:10.1016/0009-2509(87)85061-3

Cited by 157 publications

(102 citation statements)

References 13 publications

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“…Though it is helpful to run at the highest possible speeds in order to keep power losses to an acceptable level, the maximum should be less than that causing headspace gas entrainment as this can dramatically reduce Po [27]. Operating the ambr at maximum fill, air ingestion occurred at about 5500 rpm.…”

Section: Power Measurementmentioning

confidence: 99%

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Nienow

Rielly

Brosnan

et al. 2013

Biochemical Engineering Journal

113

106

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Section: Power Measurementmentioning

confidence: 99%

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Nienow

Rielly

Brosnan

et al. 2013

Biochemical Engineering Journal

113

106

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“…Consequently, extensive research has been conducted during the past decades, aimed at characterizing them and optimizing their performance. The latter has eventually led to the development and characterisation of numerous modifications of the commonly used radial impellers (see for instance [1][2][3][4][5][6][7][8][9][10][11][12]), in an effort to passively control the flow fields that they generate.…”

Section: Introductionmentioning

confidence: 99%

Effect of blade modifications on the torque and flow field of radial impellers in stirred tanks

et al. 2017

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We perform both high and low speed particle image velocimetry and torque measurements to characterize eight radial impeller types in an unbaffled stirred tank. The blade types consist of a set of regular flat blades, used as a baseline, regular blades of increased thickness, perforated blades and fractal blades. We find a qualitative correlation between the blades' torque coefficient and vortex coherence/ turbulent kinetic energy, possibly explaining the torque differences of the tested impellers. Furthermore, we find that the proposed modifications increase the bulk turbulence levels and mass flow rates, while at the same time reducing the shaft torque, showing promise for applications. Finally, we attempt a comparison between fractal and perforated geometries using data from this study and the literature.

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“…This is 239 most likely due to the fact that the 5.88" rotor is bigger and in the same size vessel, meaning that it 240 is pumping a higher flow rate of liquid. This has also been seen for Rushton and Pitched blade 241 turbines (Bujalski et al, 1987;Chapple et al, 2002). 242…”

mentioning

confidence: 56%

Scale-up of batch rotor–stator mixers. Part 1—power constants

James

Cooke

Trinh

et al. 2017

Chemical Engineering Research and Design

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7Rotor-stator mixers are characterized by a set of rotors moving at high speed surrounded closely by 8 a set of stationary stators which produces high local energy dissipation. Rotor-stator mixers are 9 therefore widely used in the process industries including the manufacture of many food, cosmetic 10 and health care products, fine chemicals, and pharmaceuticals. This paper presents data 11 demonstrating scale-up rules for the key power parameters; laminar power constant, Metzner-Otto 12 constant, and Turbulent power number; for Silverson Batch rotor-stator mixers. Part 2 of this paper 13 explores mixing times, surface aeration, and equilibrium drop sizes. These rules will allow processes 14 involving rotor-stator mixers to be scaled up from around 1 litre to over 600 litres directly. 15 Graphical abstract

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The dependency on scale of power numbers of Rushton disc turbines

Cited by 157 publications

References 13 publications

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Effect of blade modifications on the torque and flow field of radial impellers in stirred tanks

Scale-up of batch rotor–stator mixers. Part 1—power constants

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