The Demonstration of Anti-HI/HI-H Activity in Seed
Anti-H Reagents

Voak, D.; Lodge, T.W.

doi:10.1159/000466610

Cited by 3 publications

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous workers have shown that L-fucose strongly inhibits the hemag glutination of red cells by Lotus, although their testing system differs from the present system of inhibition of precipitin band formation [3,9,12,16,18]. Several workers have also shown a small amount of inhibition of red cell agglutination by Lotus with D-galactose [18] and TV-acetylglucosamine [3,9].…”

Section: Discussionmentioning

confidence: 69%

See 1 more Smart Citation

Characterization of a Human Saliva Antigen Precipitated by a Lectin from Lotus tetragonolobus

Napier¹,

Everhart²,

Grundbacher³

1974

Vox Sanguinis

View full text Add to dashboard Cite

Ouchterlony precipitin tests give visual evidence that extracts from Lotus tetragonolobus contain two different lectins. In addition to the H antigen, Lotus identifies another antigen, called the L antigen, which is not the A, B, Le^a, Sd^a, I or SC(1) saliva antigen and has been found in variable strength in secretor and nonsecretor saliva of individuals of all ABO blood groups. The L antigen is part of a cathode migrating glycoprotein. Sugar inhibition studies reveal that the terminal sugars are the same as for the H and Le^a antigens, the presumable difference being that L-fucose is attached to a different site. The L antigen is absent in the saliva and red cells of the Bombay type, but red cells of all other individuals absorb both lectins from Lotus extract.

show abstract

Section: Discussionmentioning

confidence: 69%

“…Several workers have also shown a small amount of inhibition of red cell agglutination by Lotus with D-galactose [18] and TV-acetylglucosamine [3,9].…”

Section: Discussionmentioning

confidence: 99%

Characterization of a Human Saliva Antigen Precipitated by a Lectin from Lotus tetragonolobus

Napier¹,

Everhart²,

Grundbacher³

1974

Vox Sanguinis

View full text Add to dashboard Cite

show abstract

“…Yamamoto [23] Voak et al [20] reported that lectins from C. sessilifolius and L. alpinum contained anti-HI-H agglutinin, the action of which was strongly inhibited by lactose.…”

Section: P Ostreatus Extract Agglutinated O Red Cells Most Stronglymentioning

confidence: 99%

On the Specificity of Mushroom Pleurotus ostreatus and Pleurotus spodoleucus Extracts

Kogure¹

1975

Vox Sanguinis

View full text Add to dashboard Cite

show abstract

An unusual anti-H lectin inhibited by milk from individuals with the Bombay phenotype

Joshi¹,

Vasantha

Robb³

2005

Immunohematology

View full text Add to dashboard Cite

There are several lectins with anti-H specificity but few of them serve as useful reagents. An anti-H lectin, extracted from the seeds of the plant Momordica dioica Roxb. ex willd., was tested for its hemagglutination and inhibition properties, using standard serologic methods and panel RBCs, serum, saliva, milk, and oligosaccharides purified from milk. The extract displayed strongest agglutination with group O RBCs and was weakest with group A 1 B RBCs in a spectrum of O>A 2 >B>A 2 B>A 1 >A 1 B; the extract failed to react with the RBCs from 25 individuals with the Bombay (O h ) phenotype and was inhibited by H secretor saliva, hence it was characterized as anti-H. However, its inhibition by milk samples from five mothers with the Bombay phenotype called into question its specificity as anti-H. The lectin reacted as strongly with group O ii (adult) RBCs as with normal OI RBCs, ruling out its specificity as anti-HI. Hemagglutination inhibition was observed with 2´fucosyllactose (Type 2 H) and lacto-N-fucopentose-I (Type 1 H), suggesting that the binding of the lectin had preference for H structures. However, inhibition by N-acetyllactosamine, lacto-Ntetraose, and lacto-N-neotetraose suggested that the lectin also recognized unsubstituted terminal beta-linked galactose units. The hemagglutinin property in the present lectin showed an unusual anti-H specificity. The lectin was inhibited by milk from Bombay phenotype individuals and certain milk oligosaccharides not specific for the H antigen. Immunohematology 2005;21:1-4.

show abstract

The Demonstration of Anti-HI/HI-H Activity in Seed Anti-H Reagents

Cited by 3 publications

References 4 publications

Characterization of a Human Saliva Antigen Precipitated by a Lectin from Lotus tetragonolobus

Characterization of a Human Saliva Antigen Precipitated by a Lectin from Lotus tetragonolobus

On the Specificity of Mushroom Pleurotus ostreatus and Pleurotus spodoleucus Extracts

An unusual anti-H lectin inhibited by milk from individuals with the Bombay phenotype

Contact Info

Product

Resources

About