The decrease of plaque volume during percutaneous coronary intervention has a negative impact on coronary flow in acute myocardial infarction

Abstract

The decrease in PV during PCI has a negative impact on coronary flow after PCI in patients with AMI. Embolization induced by PCI may occur in all patients with AMI.

Impact of Culprit Plaque Composition on the No-Reflow Phenomenon in Patients With Acute Coronary Syndrome An Intravascular Ultrasound Radiofrequency Analysis

“…[5][6][7][8] Indeed, our current results showed that the culprit lesions of patients with the no-reflow phenomenon tended to have a larger plaque burden and a larger RI than those in patients without the no-reflow phenomenon, although the differences were not statistically significant. In addition, our spectral analysis of IVUS RF data demonstrated that plaque composition was an important factor in the occurrence of the no-reflow phenomenon.…”

“…Previous studies have demonstrated that a large plaque burden, positive remodeling, and lipid pool-like images increase the risk for the no-reflow phenomenon. [5][6][7][8][9] However, the detailed differences in the plaque composition between patients with and without the no-reflow phenomenon have been difficult to assess with gray-scale IVUS.Recently, spectral analysis of IVUS radiofrequency (RF) data has been shown to provide detailed quantitative and Circulation Journal Vol.72, August 2008 qualitative information on the composition of coronary plaques in vivo. 10-14 A study by Nasu et al found that in vivo characterization of coronary plaques by 'virtual histology' (VH) correlated favorably with the results of in vitro histopathological examination of tissue samples obtained by directional coronary atherectomy.…”

“…Previous studies have demonstrated that a large plaque burden, positive remodeling, and lipid pool-like images increase the risk for the no-reflow phenomenon. [5][6][7][8][9] However, the detailed differences in the plaque composition between patients with and without the no-reflow phenomenon have been difficult to assess with gray-scale IVUS.…”

Target Lesion Thin-Cap Fibroatheroma Defined by Virtual Histology Intravascular Ultrasound Affects Microvascular Injury During Percutaneous Coronary Intervention in Patients With Angina Pectoris

“…[18][19][20][21][22] In addition to the effect of plaque burden, specific plaque characteristics, such as lipid pool-like image, intracoronary mural thrombus, or ultrasonic attenuation (assessed by grayscale IVUS), have been shown to be related to the no-reflow phenomenon during PCI in patients with ACS. 23- 27 Recently, radiofrequency signal-derived IVUS tissue characterization has been developed to provide objective and quantitative information for predicting distal microembolization and slow flow during PCI.…”

Atherosclerotic Plaque With Ultrasonic Attenuation Affects Coronary Reflow and Infarct Size in Patients With Acute Coronary Syndrome An Intravascular Ultrasound Study

“…3,4 Intravascular ultrasound (IVUS) is a useful tool to assess vessel lumen and plaque dimension, as well as plaque characteristics, before and after PCI. 5 Although previous reports have suggested possible IVUS predictors, such as plaque burden, 6,7 intracoronary thrombus 8 and lipid pool, 9,10 of final coronary flow and subsequent myocardial damage during primary PCI, the impact of baseline plaque characteristics on coronary flow or side-branch occlusion 11 immediately after balloon inflation and on infarct size have not been investigated.…”