The Danish Twin Register

Hauge, M.; Harvald, B; Fischer, Margit; Gotlieb-Jensen, K; Juel-Nielsen, N; Raebild, I; Shapiro, Robert; Videbech, Th.

doi:10.1017/s1120962300012749

Cited by 176 publications

(94 citation statements)

References 10 publications

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“…The Danish Twin Registry includes twin pairs born in Denmark between 1870 and 1910 and same-sex twin pairs born between 1911 and 1930 [15]. The Danish Twin Registry is the basis for the Longitudinal Study of Aging Danish Twins (LSADT), which has previously been described in detail [4].…”

Section: Study Population and Data Collectionmentioning

confidence: 99%

Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70?102

Hartvigsen

Christensen

Frederiksen

2003

European Spine Journal

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Introduction A recent survey of over 100,000 Medicare beneficiaries aged 65 and older showed that heart and lung disease and back pain (BP) were the most important factors affecting the average physical health status of older Americans [6]. Yet out of the total body of publications on BP, surprisingly little research has focused on BP in old age, and there is an under-representation of the older population in the BP literature [3]. Furthermore, the authors of the most extensive review so far dealing with the prevalence of BP in old age found that results of published studies were difficult to interpret and compare, due to varying definitions of BP among the studies [3]. Consequently, at present it is not known with certainty how common BP is in senior age groups.Little information is also available on the development and prognosis of BP over time late in life. In several cross-sectional studies the prevalence of BP has been estiAbstract Back pain (BP) has been rated among the most important factors affecting physical health status in old age. Yet there is an under-representation of the older population in the BP literature. We present extensive interview data from the Longitudinal Study of Aging Danish Twins, dealing with a population-based sample of Danish twins aged 70-102, and describing the 1-month prevalence of BP and the development of BP over time. The associations between BP and education, self-rated health, other health problems, lifestyle factors, and physical and mental function were also investigated. Data were analysed in a cross-sectional analysis for all answers given at entry into the study and in a longitudinal analysis for participants in all four surveys. Associated factors were analysed for the cross-sectional sample using univariate and multivariate analysis accounting for the non-independence of twins in complete pairs. The overall 1-month prevalence of BP was 25% and differed significantly between men and women. The variations in prevalence between the age groups and over time were negligible. The majority of participants in all four surveys had either not experienced BP during the previous month or had done so on one occasion only. Education was not associated with BP. Self-rated health was associated with BP in a significant "dose-response" like pattern. BP was associated with bone and joint disorders, migraine headaches, lung disease, cardiovascular disorders and gastric ulcer, but not neurologic or endocrinologic diseases. BP sufferers had significantly lower scores on physical but not on mental functioning. We conclude that BP is a common symptom in old age; however, the prevalence does not change with increasing age. BP may be part of a more general syndrome of poor health among the old.

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Section: Study Population and Data Collectionmentioning

confidence: 99%

Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70?102

Hartvigsen

Christensen

Frederiksen

2003

European Spine Journal

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“…The zygosity classification has been evaluated by comparison with blood group determinants, and the proportion of misclassification was less than 5%. 16 …”

Section: Study Design the Danish Twin Registrymentioning

confidence: 99%

Major Genetic Susceptibility for Venous Thromboembolism in Men: A Study of Danish Twins

Larsen

Sørensen²,

Skytthe³

et al. 2003

Epidemiology

109

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“…The Danish Twin Registry includes twin pairs born in Denmark between 1870 and 1910 and same-sex pairs born F between 1911 and 1930 (12). Our study comprised all registered Danish twins who were 75 years or older on January 1, 1995, regardless of whether the co-twin was alive, for a total of 3099 individuals.…”

Section: Study Populationmentioning

confidence: 99%

Genetic and Environmental Influences on Functional Abilities in Danish Twins Aged 75 Years and Older

Christensen

McGue

Yashin

et al. 2000

The Journals of Gerontology Series A: Biological Sciences and M

106

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The Danish Twin Register

Cited by 176 publications

References 10 publications

Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70?102

Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70?102

Major Genetic Susceptibility for Venous Thromboembolism in Men: A Study of Danish Twins

Genetic and Environmental Influences on Functional Abilities in Danish Twins Aged 75 Years and Older

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