The dangers of diagnosing cystic neck masses as benign in the era of HPV‐associated oropharyngeal cancer

Wratten, Chris; Anne, S.; Tieu, Minh Thi; Kumar, Balasubramaniam; Eisenberg, Robert

doi:10.5694/mja15.00697

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Physicians must remain vigilant in obtaining data on excessive smoking or alcohol consumption, especially in older male patients, as these are all known risk factors for upper airway malignancy. Additionally, a substantial proportion of cystic neck metastases arise from human papilloma virus-related oropharyngeal carcinoma which, unlike traditional SCC, occurs in a younger population who are frequently non-smokers and not heavy drinkers [21]. Therefore all patients aged 40 years and over should be thoroughly examined by an ear, nose and throat specialist, including endoscopy of the upper aerodigestive tract in general anesthesia.…”

Section: Discussionmentioning

confidence: 99%

“…Lekari moraju biti oprezni u prikupljanju podataka o prekomernom konzumiranju duvana ili alkohola, posebno kod muškaraca starije životne dobi, jer su to dobro poznati faktori rizika za malignitete gornjih disajnih puteva. Pored toga, značajan deo cističnih metastaza na vratu su metastaze karcinoma orofaringealne regije povezanih sa humanim papiloma virusom koji se, za razliku od tradicionalnog SCC, javlja kod mlađe populacije koji su uglavnom nepušači i ne konzumiraju velike količine alkohola [21]. Zbog toga svi pacijenti stariji od 40 godina treba da budu detaljno pregledani od strane specijaliste za uho, grlo i nos, uključujući endoskopiju gornjeg aerodigestivnog trakta u opštoj anesteziji.…”

Section: Diskusijaunclassified

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Branchial cleft cyst: What really matters?: Case report

Cukic¹,

Milenkovic²,

Dimkić-Milenković³

et al. 2022

Med gl Spec bol štit Zlatibor

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Introduction: Branchial cleft anomalies are considered to develop from the branchial apparatus that did not completely obliterate during the embryogenesis of the head and neck. These anomalies pose a significant challenge in terms of surgical management, particularly followed by misdiagnosis due to its rarity. The aim of this case report was to present the review of literature and treatment of a rare anomaly such as a second branchial cleft cyst with a particular focus on clinical as well as histopathological aspects. Case report: A 24-year-old woman was admitted to the otolaryngology department with a three-month history of painless right-sided neck swelling, following a previously resolved upper respiratory infection. The patient underwent complete excision of the cystic mass, with excellent cosmetic results and no signs of recurrence after a one-year follow-up. Conclusion: Therefore, surgery should always be the gold standard of treatment. In patients aged over 40 years, cystic metastasis from the occult head and neck primary carcinoma must be considered.

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Section: Discussionmentioning

confidence: 99%

Section: Diskusijaunclassified

Branchial cleft cyst: What really matters?: Case report

Cukic¹,

Milenkovic²,

Dimkić-Milenković³

et al. 2022

Med gl Spec bol štit Zlatibor

View full text Add to dashboard Cite

show abstract

“…12 HPV-positive head and neck cancers are more likely to present with an asymptomatic neck mass, 13 and the neck nodes are frequently cystic. These are often misdiagnosed as branchial cleft cysts, 14 leading to delayed diagnosis and delayed treatment. Given the rise of HPV-related head and neck cancer, the possibility of an incorrect diagnosis must always be considered.…”

Section: Human Papillomavirusmentioning

confidence: 99%