The daily profile of ventricular premature beats in the patients with ischemic heart disease.

Saito, Daiji; Matsuno, Shigeru; Haraoka, Shoichi

doi:10.1253/jcj.51.208

Cited by 2 publications

(1 citation statement)

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“…Myocardial infarction causes left ventricular dysfunction, thereby activating mechanoreceptors in the left ventricular wall which, in turn, would increase the traffic in afferent sympathetic fibers [19]. There is experimental evidence [20] that an increase in cardiac afferent sympathetic nerve activity causes a decrease in efferent parasympathetic nerve traffic to the heart and interferes with the baroreflex coutrol of the heart. Exercise stimulates sympathetic nerves and reduces parasympathetic nerve activity.…”

Section: Discussionmentioning

confidence: 99%

Morning increase in hemodynamic response to exercise in patients with angina pectoris

et al. 1993

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The present study was conducted to determine whether or not there is diurnal variation in the hemodynamic responses to stimuli that increase myocardial oxygen demand, and the effects of such variation on electrocardiograms (ECG). Fifteen patients with angina pectoris, 17 patients with old myocardial infarction, and 8 healthy controls were examined in this study. Graded exercise stress testing was conducted in the supine position, once in the morning and once in the afternoon, using a bicycle ergometer. A standard 12-lead ECG was recorded before, immediately after, and 3, 5, and 10 min after the end of the exercise. The exercise ECG and blood pressure changes were compared among the groups and, within each group, the results after morning and afternoon exercise were compared. Hemodynamic responses, including heart rate, blood pressure, and the pressure-rate product, showed greater increases in the morning than in the afternoon in angina patients and controls, in association with greater depression of the electrocardiographic ST-segment. In contrast, patients with old myocardial infarction exhibited no difference in hemodynamic responses or the ST-pattern from morning to afternoon. The results suggest that diurnal variation of hemodynamic responses to increased oxygen demand may explain, at least partly, why myocardial ischemia of effort angina is more severe in the morning than in the afternoon.

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Section: Discussionmentioning

confidence: 99%